DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sti and stk38l

DIOPT Version :9

Sequence 1:	NP_001261768.1	Gene:	sti / 39429	FlyBaseID:	FBgn0002466	Length:	1858	Species:	Drosophila melanogaster
Sequence 2:	NP_001006753.1	Gene:	stk38l / 448427	XenbaseID:	XB-GENE-5881027	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	440	Identity:	138/440 - (31%)
Similarity:	221/440 - (50%)	Gaps:	88/440 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 AICREGLLDAFCLLYNECDKDTLKKRD--RNIAEFVNKFRPIIEETRKLRVNADDFLIKTLIGQG 122
            |:..|||.|         |:..:::..  |...||:        ..::.|:..:||....:||:|
Frog    52 AMEEEGLGD---------DEKKMRRSQHARKETEFL--------RLKRTRLGLEDFESLKVIGRG 99

  Fly   123 YFGNVHLVVERQTNDIYAMKKIKKSVV----TTSQVKEERDIMSIRNSEWLINLQYAFQDNDNLY 183
            .||.|.||.::.|..|||||.::|:.:    ..:.::.||||:...:..|::.:.|:|||..|||
Frog   100 AFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLY 164

  Fly   184 LVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKL 248
            |:||::||||:::|:.:.....|:..:||:||..:|:..:|::|::||||||:|:|:|..||:||
Frog   165 LIMEFLPGGDMMTLLMKKDTLTEEATQFYIAETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKL 229

  Fly   249 ADFG----------------------------------NAAALDRDGHVLSLSPVGTPDYIAPEL 279
            :|||                                  .|....::...|:.|.||||||||||:
Frog   230 SDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEV 294

  Fly   280 LQTISTYKLSKSMHDVSRIVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKEL 344
            .......||            ||:||:|:|.||::....||..:...|||.|::      :.||.
Frog   295 FMQTGYNKL------------CDWWSLGVIMYEMLIGYPPFCSETPQETYRKVM------NWKET 341

  Fly   345 ISFPADLKVSVNYRNLIESLVTNPSKRL---SYERIKNHPFFSEIPWGSIRSQVPPIIP-TVRSD 405
            :.||.::..|...::||.....:...|:   ..|.||:||||..:.||.||.: |..|| .::|.
Frog   342 LVFPPEVPTSEKSKDLILRFCADSENRVGSNGVEEIKSHPFFEGVDWGHIRER-PAAIPIEIKSI 405

  Fly   406 DDTSNFEDGIRHKTRREQGVAKKSLTTNMKSNDFSGKDLPFIGYSFVHME 455
            ||||||::      ..|..:.:..|  |....|:..||..|:.|::...|
Frog   406 DDTSNFDE------FPESDILQPVL--NPPEPDYKSKDWVFLNYTYKRFE 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357	127/382 (33%)
		S_TKc	113..383	CDD:214567	102/310 (33%)
		Smc	487..1222	CDD:224117
		CNH	1503..1774	CDD:279162
stk38l	NP_001006753.1	STKc_NDR2	87..452	CDD:270776	128/388 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010