DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sti and wts

DIOPT Version :9

Sequence 1:	NP_001261768.1	Gene:	sti / 39429	FlyBaseID:	FBgn0002466	Length:	1858	Species:	Drosophila melanogaster
Sequence 2:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster

Alignment Length:	395	Identity:	140/395 - (35%)
Similarity:	209/395 - (52%)	Gaps:	74/395 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 RKLRVNADDFLIKTLIGQGYFGNVHLVVERQT-NDIYAMKKIKKSVV----TTSQVKEERDIMSI 163
            ::.:::...|:....||.|.||.|.||.:..| |.:||||.::|:.|    ..:.||.||||::.
  Fly   710 KRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAE 774

  Fly   164 RNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGY 228
            .::.|::.|.|:|||.||||.||:|:|||||:||:.:.|.|:|:|||||:||:|.|:.::|:||:
  Fly   775 ADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGF 839

  Fly   229 VHRDIKPENILIDRFGHIKLADFG---------NAAALDRDGH---------------------- 262
            :||||||:||||||.|||||.|||         |:.....:|:
  Fly   840 IHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENGPKPTV 904

  Fly   263 -----------VLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSRIVSCDYWSMGIIGYELICE 316
                       ||:.|.||||:|||||:|:.....:|            |||||:|:|.||::..
  Fly   905 LERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQL------------CDYWSVGVILYEMLVG 957

  Fly   317 TTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVTNPSKRL--SYERIKN 379
            ..||..::..||..|:::..:..|:      |...::|....:||..|..:..|||  |.:.:|:
  Fly   958 QPPFLANSPLETQQKVINWEKTLHI------PPQAELSREATDLIRRLCASADKRLGKSVDEVKS 1016

  Fly   380 HPFFSEIPWGSIRSQVPPIIPTVRSDDDTSNFEDGIRHKTRREQGVAKKSLTTNMKSNDFSGKDL 444
            |.||..|.:..:|.|..|.||.::...|||||:.....|.|...       :|....:|....|.
  Fly  1017 HDFFKGIDFADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSND-------STMSSGDDVDQNDR 1074

  Fly   445 PFIGY 449
            .|.|:
  Fly  1075 TFHGF 1079

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357	140/388 (36%)
		S_TKc	113..383	CDD:214567	120/318 (38%)
		Smc	487..1222	CDD:224117
		CNH	1503..1774	CDD:279162
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749	139/385 (36%)
wts	NP_733403.1	S_TKc	719..1020	CDD:214567	120/318 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.920