DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sti and stk38l

DIOPT Version :9

Sequence 1:	NP_001261768.1	Gene:	sti / 39429	FlyBaseID:	FBgn0002466	Length:	1858	Species:	Drosophila melanogaster
Sequence 2:	XP_005164924.1	Gene:	stk38l / 393957	ZFINID:	ZDB-GENE-040426-798	Length:	464	Species:	Danio rerio

Alignment Length:	422	Identity:	133/422 - (31%)
Similarity:	217/422 - (51%)	Gaps:	78/422 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 DKDTLKKRD---RNIAEFVNKFRPIIEETRKLRVNADDFLIKTLIGQGYFGNVHLVVERQTNDIY 139
            |::...:|.   |...||:        ..::.|:..|||....:||:|.||.|.||.::.|..||
Zfish    60 DEEKSMRRSLHARKETEFL--------RLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIY 116

  Fly   140 AMKKIKKSVV----TTSQVKEERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSR 200
            |||.::|:.:    ..:.::.||||:...:..|::.:.|:|||..||||:||::||||:::|:.:
Zfish   117 AMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMK 181

  Fly   201 HGPFDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFG------------- 252
            .....|:..:||:||..:|:.::|::|::||||||:|:|:|..||:||:|||
Zfish   182 KDTLSEEATQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSRGHVKLSDFGLCTGLKKAHRTEF 246

  Fly   253 ---------------------NAAALDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVS 296
                                 .|....::...|:.|.||||||||||:.......||
Zfish   247 YRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKL-------- 303

  Fly   297 RIVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLI 361
                ||:||:|:|.||::....||..:...|||.|::      :.:|.::||.::.:|...:.||
Zfish   304 ----CDWWSLGVIMYEMLIGYPPFCSETPQETYRKVM------NWRETLTFPPEVPISERAKELI 358

  Fly   362 ESLVTNPSKRL---SYERIKNHPFFSEIPWGSIRSQVPPIIPTVRSDDDTSNFEDGIRHKTRREQ 423
            ....|:...|:   |.:.||:||||..:.|..||.:...|...::|.||||||:|      ..|.
Zfish   359 LRYCTDAENRIGSGSVDEIKSHPFFESVDWEHIRERPAAISIDIKSIDDTSNFDD------FPES 417

  Fly   424 GVAKKSLTTNMKSNDFSGKDLPFIGYSFVHME 455
            .:.:.  ..|:..:||..||..|:.|::...|
Zfish   418 DILQP--VANVTESDFKSKDWVFLNYTYKRFE 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357	126/381 (33%)
		S_TKc	113..383	CDD:214567	102/310 (33%)
		Smc	487..1222	CDD:224117
		CNH	1503..1774	CDD:279162
stk38l	XP_005164924.1	STKc_NDR2	87..452	CDD:270776	127/387 (33%)
stk38l	XP_005164924.1	S_TKc	90..383	CDD:214567	102/310 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920