Protein Alignment sti and NBPF15

DIOPT Version :9

• Sequence 1: NP_001261768.1
• Gene: sti / 39429
• FlyBaseID: FBgn0002466
• Length: 1858
• Species: Drosophila melanogaster
• Sequence 2: NP_001372377.1
• Gene: NBPF15 / 284565
• HGNCID: 28791
• Length: 698
• Species: Homo sapiens
• Alignment Length: 628
• Identity: 127/628 - (20%)
• Similarity: 250/628 - (39%)
• Gaps: 166/628 - (26%)

  Fly   564 LNRQKYEEAKIASEQRYEKQLADKKQELASTLQK---------LDARELEFNAKFEECKHL-SMK 618
            |:.:|.|...:...::...|||:|||:..:..:|         |..|:.::  |:||||.| ...
Human     8 LSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKY--KYEECKDLIKFM 70

  Fly   619 LQNYKDMLQQIKEQNLKSETNHEEQRRQ---MAELYEQKLTDLRKKVRDSQDTNRRMTMEIKEIR 680
            |:|.:    |.||:.|..:....|:.||   :....|::||.||:|:|:.:|.:|.:...::.:.
Human    71 LRNER----QFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALL 131

  Fly   681 TELDESISSSKSTQEAKNATERNIEEILRRLNEEIASNNELHAEKVKLETKLQLKENETQEVRAE 745
            |..:...|..:..||......|..:.::::|:.| ..|::....:|::..|:|......:..:||
Human   132 TPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPE-NDNDDDEDVQVEVAEKVQKSSAPREMQKAE 195

  Fly   746 CHRLEREL---QLAECRCQLAESSLATQVSPYET-APGSLTELNAIEDQLRADLLAAKESENHQK 806
                |:|:   .|.||....:.|.     .||:: .|...|::...||::.:.|:.   |.:|.:
Human   196 ----EKEVPEDSLEECAITCSNSH-----GPYDSNQPHKKTKITFEEDKVDSTLIG---SSSHVE 248

  Fly   807 GRADQLQTLVTKLEQMLERFNEQSLSPTKSHSSRKQEGETVGDMLERQNEKLEDKLAAVREQMIV 871
            .                    |.::.....:.|..:|.|..|.:..|..::..:..:
Human   249 W--------------------EDAVHIIPENESDDEEEEEKGPVSPRGMDEAGNHHS-------- 285

  Fly   872 ERQAARTANLSLWKVEKQLEEALSEKKLLARRMELTEDRIKKVQNASDEAQRMLKTSQEETRQRE 936
            ::..|||.|        |:...|:.:.|                                   :|
Human   286 QQTIARTKN--------QIPHVLTHRNL-----------------------------------QE 307

  Fly   937 SRIEELKQELAAAKRDVLKEHRQWEKAEQERMKCKSEII----EHLANVHRLEQQETELRQKLRQ 997
            |..||:.||             .|::. ...:....|::    .:.:..|.||:|:..:...:.
Human   308 SEEEEVPQE-------------SWDEG-YSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG- 357

  Fly   998 IQSRFDGVTLEQKNTI-----RELQEEREKS--RKANDSCLVLQKELKQLTDNFQRLKYACSITD 1055
             :.|:|.|..|.:...     |||.:|:|..  :.:.|.|........:|||:.|..:.|..:.:
Human   358 -RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 421

  Fly  1056 SQ-------LTEVETMLKSEQERNKS-QKSQLDTLHEK----LRERND----------QLTDLRK 1098
            .|       :.|:|...:.|::::.| .:...:.|.||    |::..|          :|.||.:
Human   422 QQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQ 486

  Fly  1099 QLTTVESEKRLAEQRAQVLASEIDELRLNLKEQQKKLVAQQDQ 1141
            ..:   |.....|::...||.::|.::   |:|::    ::||
Human   487 PYS---SAVYSLEEQYLGLALDVDRIK---KDQEE----EEDQ 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357
		S_TKc	113..383	CDD:214567
		Smc	487..1222	CDD:224117	127/628 (20%)
		CNH	1503..1774	CDD:279162
NBPF15	NP_001372377.1	DUF1220	179..240	CDD:399619	16/69 (23%)
		DUF1220	<316..353	CDD:399619	7/50 (14%)
		DUF1220	366..429	CDD:399619	14/62 (23%)
		DUF1220	439..504	CDD:399619	13/67 (19%)
		DUF1220	514..579	CDD:399619	2/10 (20%)
		DUF1220	610..672	CDD:399619

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000