Protein Alignment sti and mks-5

DIOPT Version :9

• Sequence 1: NP_001261768.1
• Gene: sti / 39429
• FlyBaseID: FBgn0002466
• Length: 1858
• Species: Drosophila melanogaster
• Sequence 2: NP_001254260.1
• Gene: mks-5 / 174654
• WormBaseID: WBGene00007490
• Length: 1322
• Species: Caenorhabditis elegans
• Alignment Length: 1136
• Identity: 215/1136 - (18%)
• Similarity: 399/1136 - (35%)
• Gaps: 366/1136 - (32%)

  Fly   595 LQKLDARELEFNAKFEECKHLSMKLQNYKDMLQQIKEQNLKSETNHEEQRRQMAELYEQ--KLTD 657
            ::|....:||        .|....::......:::|||..:..|.:...||.|.|...|  |:.:
 Worm     8 IEKWSRPQLE--------DHFHNVVEELNKAQKKVKEQEKQITTFNSRFRRSMLERKSQNEKVVE 64

  Fly   658 LRKKVRDSQDTNRRMTMEIKEIRTEL-----------DESISSSKSTQEAKNATER--------N 703
             |.|..|....|:.:.|::|..:.:|           ..|:.:.:||.....:|.|        .
 Worm    65 -RSKYDDVVKENQILDMKLKAAKQQLLIYTAPSARATTASMMTGRSTFRQPPSTFRQRPPLTAGT 128

  Fly   704 IEEILRRLNEEIASNNELHAEKVKLETKLQLK--------ENETQEVRAECHRLERELQLAECRC 760
            ...|.|..:..:|.......||::|.|..:|.        :|:..|:....:.:|:   |.:.:.
 Worm   129 TGSIDRPGSAPVARKKSDGGEKLQLATDEKLAIVRLNRTLKNKNDEITELKYTIEK---LRQLKS 190

  Fly   761 QLAESSLATQVSPYETAPGSLTELNAIEDQLRADLLAAKESENHQKGRADQLQTLVTKLEQMLER 825
            .:.:||..|::|...::..|                   .|.|:..|....     ::||:|.|.
 Worm   191 SVNQSSPPTRLSTSSSSKSS-------------------SSNNNNDGEGKD-----SELEEMSEM 231

  Fly   826 FNEQSLSPT-----------KSHSSRKQE---GETVGDMLERQNEKL--------EDKLAAVREQ 868
            .:::|...|           ||..|..||   .......:..|.||:        |:.||.::|:
 Worm   232 SDDESGRSTPVIEEKKKPRRKSRKSSHQEPSKNPIPPPRIPDQTEKVLLDKLKVAENDLAMLQEE 296

  Fly   869 M-IVERQAARTANLSLWK-VEKQLEEALSEKKLLARRMEL---TEDRIKKVQNASDEAQRMLKTS 928
            . :|::...|..:.||.| .|....|::.|||.:....||   ||.|||:.::...|.|:..:..
 Worm   297 CDLVKKANERLVHQSLSKSTEYGARESIEEKKKIVELEELLKETEKRIKESEHRRREDQKKFEAM 361

  Fly   929 QEETRQRESRIEELKQELAAAKRDVLKEHRQWEKAEQERMKCKSEIIEH---------------L 978
            :...:.:....::.:::|:...::        .|.|:||:  :.|.|.|               .
 Worm   362 RLHYKNKYDAAKKTEKKLSVVAKN--------SKVEEERI--EEEKISHSPPPMTFEPIRKRHSQ 416

  Fly   979 ANVHRLEQQETELRQKL----RQIQSRFDGVTLEQKNTI--------------RELQEEREKSRK 1025
            :.:.|:.:.:.:|.|||    ..|....| |.:.:.||:              .||.||.||.|
 Worm   417 SEISRMRRADDDLLQKLYKEVADILHSHD-VGIAEINTLGASENSLARWQKLYSELYEELEKVR- 479

  Fly  1026 ANDSCLVLQKELKQLTDNFQRLKYACSITDSQLTEVETMLKSEQERNKSQKSQ-LDTLHEKLRER 1089
               :.|::|.::.|                .|:.|:: :||.|.:|.|:..:: |....|::.||
 Worm   480 ---NMLLIQYDINQ----------------KQMKEIK-LLKDELDRLKTVSAEILSKSREEVEER 524

  Fly  1090 NDQLTDLRKQLTTVESEKRLAEQRAQVLASEID--ELRLNLKEQQKKLVAQQDQLVEQTNALFAT 1152
            ..::..|.:|:.|:...   .:|..::||::|:  ..|:| .:...||:..:......:...|:.
 Worm   525 QKKIFMLEEQIRTIAYS---GQQPVKLLANQINIPTPRVN-TDLSVKLINVKPSPSLTSKFFFSL 585

  Fly  1153 Q------ERAELLDGQNANYEAQT----------------------------------ADSNREM 1177
            :      |...::|.:..|.:..|                                  |.:...:
 Worm   586 EFFDFQLETTPIMDAKQHNMDFTTVYDVLVSNLLIHYLQTNGIVIEMYRPASDCYKLLAAATISL 650

  Fly  1178 VSLKEENA--RILSELFHKKEEVGNLQAEIRGLESAQANLHAEIDS-LQDTLAEKEQFYVQRDIK 1239
            :.|.|::.  :..||:..|..:.        |:|........|:.. :.|:..:.::..:.|::.
 Worm   651 IPLFEDSVLRKFCSEIMLKSVDT--------GVEMCTLRYEIEVSQPISDSFKKFKKSEMARNML 707

  Fly  1240 SNATLAQHKKLIDYLQLKVED--------LSAKKKKTLADKLFGSSHTNK-------ENVSP--N 1287
            .             |||:.||        |:....:.:....||...:.:       .:.||  .
 Worm   708 P-------------LQLENEDTEDTNFDPLTIMVNRVVGLDTFGKDPSTEFCIVDEFLSFSPYFT 759

  Fly  1288 DVESSILYRALKE----------ELKREQKMNSLLKEQLAQLNGT-ATLRSP-----RKSAAVNG 1336
            |..:|...|:.::          .|.....::..|.|.:.:.:|. |||..|     :...::.|
 Worm   760 DFSTSSEIRSKRDCYIPKIDIARNLFATSSISFFLIENIPRQDGVIATLHLPLHPLCKLGGSIKG 824

  Fly  1337 -----DSDAPKQRPVSIAA-----------------LPRSPQKQ-------QQPLKRTTSQVELK 1372
                 |:|.   ||.|::.                 .|:.|.|:       .||::||:     |
 Worm   825 TFPMLDTDG---RPSSVSLDLCLIWKHEIPSFFLKHEPKEPLKEVKDTPILPQPVRRTS-----K 881

  Fly  1373 TTAEKPTKVTIENQAHHRFELALQESKVDAVNCVVCEKAVVAGSPFWKCKECKDVTHRKCRSNVQ 1437
            .....|.|   |.:.|            ||....:..||
 Worm   882 EFVVTPVK---EAELH------------DAEPTSMPPKA-------------------------- 905

  Fly  1438 SHCGSTKPTAPSADDLSSIQSVSSLTLDSVDVAGGTTSGGEY------IGSLVYSSDGAEDQAR- 1495
                 .:||......||:..|.:|.:..|.|:....|:...|      :...:..|||.|:..|
 Worm   906 -----PEPTTAPLRRLSTDSSDTSFSHSSKDLFSPPTNPQTYDYEIPAVTPALVDSDGEEEADRI 965

  Fly  1496 ------KEIEVNCA---------FEVAEQQI 1511
                  .|||...|         .||.|:|:
 Worm   966 VFDDDDDEIESVSAVSSQRDPEPLEVPERQV 996

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357
		S_TKc	113..383	CDD:214567
		Smc	487..1222	CDD:224117	147/761 (19%)
		CNH	1503..1774	CDD:279162	5/18 (28%)
mks-5	NP_001254260.1	C2-C2_1	<591..688	CDD:288470	13/104 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000