DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sti and wts-1

DIOPT Version :9

Sequence 1:	NP_001261768.1	Gene:	sti / 39429	FlyBaseID:	FBgn0002466	Length:	1858	Species:	Drosophila melanogaster
Sequence 2:	NP_492699.1	Gene:	wts-1 / 172896	WormBaseID:	WBGene00007047	Length:	908	Species:	Caenorhabditis elegans

Alignment Length:	426	Identity:	135/426 - (31%)
Similarity:	215/426 - (50%)	Gaps:	93/426 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 CREGLLDAFCLLYNECDKDTLKKRDRNIAEFV-------------NKFRPIIEE-------TRKL 106
            |:..:|..:...:.|......|:|::.:.:..             ||...::::       .|:.
Worm   431 CKPNMLRFYMEQHVERLLQQYKEREKRMKQLEKEMVSAQLPDIMRNKMLGLLQQKESKYTRLRRQ 495

  Fly   107 RVNADDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTTSQ----VKEERDIMSIRNSE 167
            :::...|.:.:.||.|.||.|.||.:..|..:||||.::|:.|...|    ||.||||::..:|.
Worm   496 KMSKSHFTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSP 560

  Fly   168 WLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGYVHRD 232
            |::.|.::|||:..||.:|||:||||:::|:.:.|.|:|||||||:|||..|:..:|.:|::|||
Worm   561 WIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEEDLARFYIAELACAIEYVHNVGFIHRD 625

  Fly   233 IKPENILIDRFGHIKLADFG------------------------------NAAALDRDGHVLSL- 266
            :||:|||||:.|||||.|||                              ..||:|:...||::
Worm   626 LKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRVDSFSLPPEVAAIDKSVKVLNVR 690

  Fly   267 ---------SPVGTPDYIAPELLQTISTYKLSKSMHDVSRIVSCDYWSMGIIGYELICETTPFHE 322
                     |.|||.:|:|||:        ::|:.|:    .|||:||.|:|.||::....|||:
Worm   691 QQTRRITAHSLVGTGNYMAPEV--------IAKTGHN----QSCDWWSTGVILYEMVFGRVPFHD 743

  Fly   323 DNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVTNPSKRLSYE---------RIK 378
            |....|..:|      .:.:..:.|.....:|.....:|:.|:.:.|.||...         ::|
Worm   744 DTPGGTQHRI------KNWRNFLDFTYCGNLSKECLMMIQQLICDASSRLGSHGKDVAERTAQVK 802

  Fly   379 NHPFFSEIPWGSIRSQVPP--IIPTVRSDDDTSNFE 412
            |||:|..|.|.::|.....  .||.|..|:||||||
Worm   803 NHPWFRGIDWVNLRKLRADYIYIPRVTHDEDTSNFE 838

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357	127/357 (36%)
		S_TKc	113..383	CDD:214567	113/322 (35%)
		Smc	487..1222	CDD:224117
		CNH	1503..1774	CDD:279162
wts-1	NP_492699.1	STKc_LATS	500..868	CDD:270749	127/357 (36%)
wts-1	NP_492699.1	S_TKc	502..807	CDD:214567	113/322 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920