Protein Alignment sti and Mad1l1

DIOPT Version :9

• Sequence 1: NP_001261768.1
• Gene: sti / 39429
• FlyBaseID: FBgn0002466
• Length: 1858
• Species: Drosophila melanogaster
• Sequence 2: XP_036020731.1
• Gene: Mad1l1 / 17120
• MGIID: 1341857
• Length: 725
• Species: Mus musculus
• Alignment Length: 780
• Identity: 164/780 - (21%)
• Similarity: 321/780 - (41%)
• Gaps: 170/780 - (21%)

  Fly   682 ELDESISSSKSTQEAKNATERNIE-----EILRRLNEEIASNNELHAEKVKLETKLQLKENETQE 741
            :|.|:.:...|.:...|...:.:|     ::....:..:....|.|   ::||.:.:...:::..
Mouse     3 DLGENTTVLSSLRSLNNFISQRMEGTSGLDVSTSASGSLQKQYEYH---MQLEERAEQIRSKSYL 64

  Fly   742 VRAECHRLERELQLAECRCQLAESSLATQVSPYETAPGSLTELNAIEDQLRADLLAAKESENHQK 806
            ::.|..:::.||.....|.:| |.:.:|....||                       :|.:.:|:
Mouse    65 IQVEREKMQMELSHKRARVEL-ERAASTNARNYE-----------------------REVDRNQE 105

  Fly   807 --GRADQLQ----TLVTKLEQMLERFNEQSLSPTKSHSSRKQEGETVGDMLERQNEKLEDKLAAV 865
              .|..|||    |...|:.:.|||           |...||..:.|...|..|    ||.||:.
Mouse   106 LLARIRQLQECEATAEEKMREQLER-----------HRLCKQNLDAVSQQLREQ----EDSLASA 155

  Fly   866 REQMIVERQAARTANLSLWKVEK--QLEEALSEKKLLARRMELTEDRIKKVQNASDEAQRMLKTS 928
            ||  ::.....|.:.|.|..:::  |::...|||:.|..::||.:   :|.|.|:.:.|. |:.|
Mouse   156 RE--MISSLKGRVSELQLSAMDQKVQVKRLESEKQELKEQLELQQ---RKWQEANQKIQE-LQAS 214

  Fly   929 QEETRQRESRIEELKQELAAAKRD--VLKEHRQWEKAEQERM-KCKSEIIE-HLANVHRLEQQET 989
            |:|..:.|.:|::|:|:|...::|  |:|.    .|:|..|| :.:.|:.. |..|.|..|.:||
Mouse   215 QDERAEHEQKIKDLEQKLCLQEQDAAVVKS----MKSELMRMPRMERELKRLHEENTHLREMKET 275

  Fly   990 E---------LRQKL---RQIQSRFDGVTLEQKNTIRELQ--EEREKSRKANDSCLVLQKELKQL 1040
            .         |::||   .::|.....:.||::..:.:||  |..:::...|   |...::|.:.
Mouse   276 NGLLTEELEGLQRKLSRQEKMQEALVDLELEKEKLLAKLQSWENLDQTMGLN---LRTPEDLSRF 337

  Fly  1041 TDNFQRLKYACSITDSQLTEVETMLKSEQERNKSQKSQLDTLHEKLRERNDQLTDLRKQLTTVES 1105
            ....|:.:......::.:|.....|:..|::          |.:::|:.|.||.:.||:..|.|:
Mouse   338 VVELQQRELTLKEKNNSITSSARGLEKVQQQ----------LQDEVRQANAQLLEERKKRETHEA 392

  Fly  1106 EKRLAEQRAQVLASEIDELRLNLKEQQKKLVAQQDQLVEQTNALFATQERAELLDGQNANYEAQT 1170
            ..|..::|..:|..|.|.:|..|.....:| .|.:...:.|..|:..::..:.:...::..|||.
Mouse   393 LARRLQKRNALLTKERDGMRAILGSYDSEL-TQTEYSTQLTQRLWEAEDMVQKVHAHSSEMEAQL 456

  Fly  1171 ADSNREMVSLKEENARILSELFHKKEEVGNLQAEIRGLESAQANLHAEIDSLQDTLAEKEQFYVQ 1235
            :.:              |.||..:|:....|:.|::.|::            |.:.||
Mouse   457 SQA--------------LEELGVQKQRADTLEMELKMLKA------------QTSSAE------- 488

  Fly  1236 RDIKSNATLAQHKKLIDYLQLKVEDLSAKKKKTLADKLFGSSHTNKENVSP--NDVESSILYRAL 1298
                  ::.:..|:.:|.|:||||:|..::.:...:|........|..:..  |...:.:|:.:|
Mouse   489 ------SSFSFCKEEVDALRLKVEELEGERSRLEQEKQVLEMQMEKLTLQGDYNQSRTKVLHMSL 547

  Fly  1299 KE---ELKREQKMNSLLKEQLAQLNGTATLRSPRKSAAVNGDSDAPKQRPVS--IAALPR---SP 1355
            ..   ..:|:.:.:..|:|:..:|.|  .:.:..:...:..|.:|....|.|  :|.|.:   |.
Mouse   548 NPISMARQRQHEDHDRLQEECERLRG--LVHALERGGPIPADLEAASSLPSSKEVAELRKQVESA 610

  Fly  1356 QKQQQPLKR--------------TTSQVELKTTAEKPTKVTIENQAHH--------RFELALQES 1398
            :.:.|.||.              |.:..::..|.|...::|.....|.        :.:|.||.|
Mouse   611 ELKNQRLKEVFQTKIQEFRKVCYTLTGYQIDVTTESQYRLTSRYAEHQTDCLIFKGKNQLELQSS 675

  Fly  1399  1398
            Mouse   676  675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357
		S_TKc	113..383	CDD:214567
		Smc	487..1222	CDD:224117	124/570 (22%)
		CNH	1503..1774	CDD:279162
Mad1l1	XP_036020731.1	MAD	54..665	CDD:368498	151/714 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000