Protein Alignment CG10654 and ZNF142

DIOPT Version :10

• Sequence 1: NP_001261767.1
• Gene: CG10654 / 39428
• FlyBaseID: FBgn0036294
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: NP_001353219.1
• Gene: ZNF142 / 7701
• HGNCID: 12927
• Length: 1887
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 81/367 - (22%)
• Similarity: 118/367 - (32%)
• Gaps: 136/367 - (37%)

  Fly    54 HNLDSEQDLASKYYGCTGE-DAVRDLPPQLVLKSICE--CCYQLV----QKFHDFQRM-----CA 106
            |.|:..::.::......|: ||.:  ||  :....|:  |.:|||    .|.|...|:     ||
Human  1598 HYLEQHEETSAAVAASDGDGDAGQ--PP--LHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCA 1658

  Fly   107 ESLRNFEKLLQDIDIGCHKLEDHTWHDLDTPSESNESTNPEAQSHAPCIAATQEIVSFIWPQVCL 171
            .|.:|.:|:              |||
Human  1659 YSTKNRQKI--------------TWH--------------------------------------- 1670

  Fly   172 PLAVILSRITLGASLEEEVYVIEDESAKQDLGQEKLSISSKLLGARKRRGVRHTLECRICHRGFY 236
                  |||..|    |:.|                                   .|.:|.....
Human  1671 ------SRIHTG----EKPY-----------------------------------HCHLCPYACA 1690

  Fly   237 KPSLLEAHMQQHEGLRPYTCVHCAKSYARANLLESHLRQMHNNADAARIIYACPSCNKVYTANR- 300
            .||.|:.||:.|:..|.|.|..|.......|.|:.|:.: |.....    |.||.|.  |..||
Human  1691 DPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTK-HTGLKP----YQCPECE--YCTNRA 1748

  Fly   301 -SLKYHMRRTHERYHESESPDAR-HICEECGKCFARKAHLTRHKMVHGSVEGRRYCCECCDRRFY 363
             :|:.|....|.        :|| .:||:|||.|..:..|..|...|.  |.:.|.|..|.|.|.
Human  1749 DALRVHQETRHR--------EARAFMCEQCGKAFKTRFLLRTHLRKHS--EAKPYVCNVCHRAFR 1803

  Fly   364 TKENMVDHLLRKHGNKNLLLRCRKCGRIFQNSVELNAHGRKH 405
            ....:..|.| .|.:::... ||.|....:...::..|.|:|
Human  1804 WAAGLRHHAL-THTDRHPFF-CRLCNYKAKQKFQVVKHVRRH 1843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10654	NP_001261767.1	zf-AD	39..115	CDD:462262	19/72 (26%)
		C2H2 Zn finger	228..248	CDD:275368	7/19 (37%)
		SFP1	<243..310	CDD:227516	20/68 (29%)
		C2H2 Zn finger	256..313	CDD:275368	16/58 (28%)
		SFP1	<287..376	CDD:227516	29/91 (32%)
		C2H2 Zn finger	289..314	CDD:275368	9/26 (35%)
		C2H2 Zn finger	325..345	CDD:275368	8/19 (42%)
		C2H2 Zn finger	355..376	CDD:275368	6/20 (30%)
		C2H2 Zn finger	385..405	CDD:275368	5/19 (26%)
ZNF142	NP_001353219.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		C2H2 Zn finger	365..385	CDD:275368
		C2H2 Zn finger	393..413	CDD:275368
		C2H2 Zn finger	421..438	CDD:275368
		C2H2 Zn finger	455..475	CDD:275368
		C2H2 Zn finger	545..566	CDD:275368
		C2H2 Zn finger	574..595	CDD:275368
		zf-H2C2_5	601..625	CDD:404746
		C2H2 Zn finger	603..623	CDD:275368
		C2H2 Zn finger	631..651	CDD:275368
		C2H2 Zn finger	659..679	CDD:275368
		C2H2 Zn finger	687..707	CDD:275368
		C2H2 Zn finger	714..731	CDD:275368
		PHA03247	928..>1219	CDD:223021
		C2H2 Zn finger	1306..1353	CDD:275368
		C2H2 Zn finger	1373..1394	CDD:275368
		C2H2 Zn finger	1402..1422	CDD:275368
		C2H2 Zn finger	1430..1451	CDD:275368
		C2H2 Zn finger	1626..1646	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1654..1674	CDD:275368	10/78 (13%)
		C2H2 Zn finger	1682..1702	CDD:275368	7/19 (37%)
		zf-H2C2_2	1694..1718	CDD:463886	8/23 (35%)
		C2H2 Zn finger	1710..1730	CDD:275368	5/20 (25%)
		zf-H2C2_2	1723..1747	CDD:463886	8/30 (27%)
		C2H2 Zn finger	1738..1759	CDD:275368	8/22 (36%)
		C2H2 Zn finger	1767..1787	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1795..1815	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1823..1843	CDD:275368	5/19 (26%)