DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10654 and CG30020

DIOPT Version :9

Sequence 1:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_610627.2	Gene:	CG30020 / 36156	FlyBaseID:	FBgn0050020	Length:	1309	Species:	Drosophila melanogaster

Alignment Length:	183	Identity:	54/183 - (29%)
Similarity:	79/183 - (43%)	Gaps:	21/183 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 DESAKQDLGQEKLSISSKLLGARKRRGVRHTLECRICHRGFYKPSLLEAHMQQHEGLRPYTCVHC 259
            ||..|  |.:.::.:.|..  .|.|.|.:|  :|.||:..:...:||:.||::|.. |...|..|
  Fly  1097 DELGK--LVKHEMELHSNT--ERSRWGYQH--KCAICNTSYRTLTLLKFHMKRHSN-RKSQCKLC 1154

  Fly   260 AKSYARANLLESHLRQMHNNADAARIIYACPSCNKVYTANRSLKYHMRRTHERYHESESPDARHI 324
            .||:.....||.|.:..|:.....|..  ...|.|.:    :.|:|:.|..:..|.|    .|:|
  Fly  1155 PKSFVTIAELERHTKAKHSKDKTLRCF--MDGCRKTF----AFKHHLIRHQKASHLS----TRYI 1209

  Fly   325 CEECGKCFARKAHLTRHKMVH-GSVEGRRYCCECCDRRFYTKENMVDHLLRKH 376
            |..|.|......||..|..|| |.:   .|.|..|||.:..:..:|.|.|..|
  Fly  1210 CPVCNKEEKSNVHLKNHMSVHKGEI---TYKCPKCDRSYLRRGRLVTHALIIH 1259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071
		C2H2 Zn finger	228..248	CDD:275368	7/19 (37%)
		C2H2 Zn finger	256..313	CDD:275368	14/56 (25%)
		C2H2 Zn finger	289..314	CDD:275368	5/24 (21%)
		zf-C2H2	323..345	CDD:278523	7/21 (33%)
		C2H2 Zn finger	325..345	CDD:275368	6/19 (32%)
		C2H2 Zn finger	355..376	CDD:275368	7/20 (35%)
		C2H2 Zn finger	385..405	CDD:275368
CG30020	NP_610627.2	zf-AD	25..106	CDD:285071
		C2H2 Zn finger	369..389	CDD:275368
		C2H2 Zn finger	397..418	CDD:275368
		C2H2 Zn finger	442..460	CDD:275368
		C2H2 Zn finger	730..750	CDD:275368
		C2H2 Zn finger	758..777	CDD:275368
		C2H2 Zn finger	1089..1110	CDD:275368	4/14 (29%)
		C2H2 Zn finger	1124..1144	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1151..1172	CDD:275368	7/20 (35%)
		C2H2 Zn finger	1180..1203	CDD:275368	5/28 (18%)
		C2H2 Zn finger	1210..1230	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1238..1254	CDD:275368	5/15 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440006
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840