DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10654 and CG1602

DIOPT Version :9

Sequence 1:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_610291.2	Gene:	CG1602 / 35684	FlyBaseID:	FBgn0033186	Length:	577	Species:	Drosophila melanogaster

Alignment Length:	337	Identity:	72/337 - (21%)
Similarity:	113/337 - (33%)	Gaps:	113/337 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 QDLASKYY---------GCTGE----DAVRDLPPQLV-LKSICECCYQLVQKFHDFQRMCAESLR 110
            |:|...||         |.|.|    :..|.:|.::. .:.:||.|:|:....|..|
  Fly   325 QNLRQWYYKNTKHAIYAGSTAEKFYLEVCRFMPAKMYKQRLVCEFCHQITSSDHVLQ-------- 381

  Fly   111 NFEKLLQDIDIGCHKLEDHTWHDLDTPSESNESTNPEAQSHAPCIAATQEIVSFIWPQVCLPLAV 175
                        .|..:.|...:|  |.:              |....:..|.     .| .||.
  Fly   382 ------------SHIFKAHNIGEL--PFK--------------CTLCDRSFVG-----RC-ELAN 412

  Fly   176 ILSRITLGASLEEEVYVIEDESAKQDLGQEKLSISSKLLGARKRRGVRHTLECRICHRGFYKPSL 240
            .:.|:.:|                                        .|.:|..|.|.|...|.
  Fly   413 HIQRVHIG----------------------------------------KTHKCTHCERSFAVMSD 437

  Fly   241 LEAHMQQHEGLRPYTCVHCAKSYARANLLESHLRQMHNNADAARIIYACPSCNKVYTANRSLKYH 305
            |:.|::.|.|.:||.|.||.|::...:.:..|:..:|....|    :.|..|.|.:.....|..|
  Fly   438 LQLHIRTHTGHKPYVCEHCGKAFRLRSQMTLHVTAIHTKIRA----FKCTMCPKDFVKKVDLSDH 498

  Fly   306 MRRTHERYHESESPDARHICEECGKCFARKAHLTRHKMVHGSVEGRRYCCECCDRRFYTKENMVD 370
            : :.|....:.       ||..|||.|.....|.||:.:|..|  :::.|:.||.||.....:..
  Fly   499 I-KGHLNIRDK-------ICSVCGKGFTSCHALIRHRQIHSEV--KKFVCKLCDSRFSQFVGLNT 553

  Fly   371 HLLRKHGNKNLL 382
            |:.|.|   |:|
  Fly   554 HMKRTH---NIL 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071	15/68 (22%)
		C2H2 Zn finger	228..248	CDD:275368	7/19 (37%)
		C2H2 Zn finger	256..313	CDD:275368	13/56 (23%)
		C2H2 Zn finger	289..314	CDD:275368	6/24 (25%)
		zf-C2H2	323..345	CDD:278523	9/21 (43%)
		C2H2 Zn finger	325..345	CDD:275368	8/19 (42%)
		C2H2 Zn finger	355..376	CDD:275368	7/20 (35%)
		C2H2 Zn finger	385..405	CDD:275368
CG1602	NP_610291.2	GT1	157..244	CDD:304916
		MADF_DNA_bdg	273..356	CDD:287510	8/30 (27%)
		C2H2 Zn finger	367..388	CDD:275368	7/40 (18%)
		C2H2 Zn finger	397..418	CDD:275368	6/26 (23%)
		COG5048	<423..554	CDD:227381	40/144 (28%)
		C2H2 Zn finger	425..445	CDD:275368	7/19 (37%)
		zf-H2C2_2	437..460	CDD:290200	10/22 (45%)
		C2H2 Zn finger	453..470	CDD:275368	4/16 (25%)
		C2H2 Zn finger	482..502	CDD:275368	5/20 (25%)
		C2H2 Zn finger	510..530	CDD:275368	8/19 (42%)
		C2H2 Zn finger	538..559	CDD:275368	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440004
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930