DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10654 and fezf-1

DIOPT Version :9

Sequence 1:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_502594.2	Gene:	fezf-1 / 3564888	WormBaseID:	WBGene00012639	Length:	218	Species:	Caenorhabditis elegans

Alignment Length:	182	Identity:	50/182 - (27%)
Similarity:	82/182 - (45%)	Gaps:	17/182 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 RHTLECRICHRGFYKPSLLEAHMQQHEGLRPYTCVHCAKSYARANLLESHLRQMHNNADAARIIY 287
            |....|.||.:.|.....|..||..|.|.||:.|..|.|::.:|:.|..| :.:|.::..    :
Worm    49 RKKFPCEICGKQFNAHYNLTRHMPVHTGERPFVCKVCGKAFRQASTLCRH-KIIHTDSKP----H 108

  Fly   288 ACPSCNKVYTANRSLKYHMRRTHERYHESESPDARHICEECGKCFARKAHLTRHKMVHGSVEGRR 352
            .|.:|.|.:..:.:|     .||.|.|:...|   .:||.|||.|.:..:...|::.|  .:.::
Worm   109 KCKTCGKCFNRSSTL-----NTHVRIHQGFKP---FVCEICGKGFHQNGNYKNHRLTH--EDTKK 163

  Fly   353 YCCECCDRRFYTKENMVDHLLRKHGNKNLLLRCRKCGRIFQNSVELNAHGRK 404
            :.|..|.|.|:...|:..|:.....:|.  ..|..|.:.|..:.:|..|.||
Worm   164 FSCSICSRAFHQSYNLAFHMFTHEEHKP--FTCHVCSKGFCRNFDLKKHLRK 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071
		C2H2 Zn finger	228..248	CDD:275368	7/19 (37%)
		C2H2 Zn finger	256..313	CDD:275368	13/56 (23%)
		C2H2 Zn finger	289..314	CDD:275368	7/24 (29%)
		zf-C2H2	323..345	CDD:278523	7/21 (33%)
		C2H2 Zn finger	325..345	CDD:275368	7/19 (37%)
		C2H2 Zn finger	355..376	CDD:275368	6/20 (30%)
		C2H2 Zn finger	385..405	CDD:275368	7/20 (35%)
fezf-1	NP_502594.2	COG5048	<13..212	CDD:227381	48/179 (27%)
		DUF3449	<50..>70	CDD:288759	5/19 (26%)
		C2H2 Zn finger	54..74	CDD:275368	7/19 (37%)
		zf-H2C2_2	66..91	CDD:290200	10/24 (42%)
		C2H2 Zn finger	82..102	CDD:275368	6/20 (30%)
		C2H2 Zn finger	110..130	CDD:275368	7/24 (29%)
		C2H2 Zn finger	138..158	CDD:275368	7/19 (37%)
		C2H2 Zn finger	166..186	CDD:275368	6/19 (32%)
		C2H2 Zn finger	194..212	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000