DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10654 and CG30431

DIOPT Version :9

Sequence 1:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	442	Identity:	97/442 - (21%)
Similarity:	160/442 - (36%)	Gaps:	110/442 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 MICRACLVLLGPQDACHNL-DSEQDLASKYYGCTGEDAVRDLPPQLVLKS-------ICECCYQL 94
            ::||.||:...|  ..|:| |:...||.:         ::.|.|.|.|:.       ||:.|.:.
  Fly    10 LVCRCCLLEQPP--LYHSLYDASSQLAVE---------LKALAPALRLEHGDNLTDVICDLCLRR 63

  Fly    95 VQKFHDFQRMCAES--------------------------LRNFEK------------------- 114
            :....||||.|..|                          |...|:
  Fly    64 LHDARDFQRRCEHSEQVLRMRHEHWKHTVAVGDALALDDVLECLEREVGSLEGPMSVPLQASKPV 128

  Fly   115 -----LLQDIDIGCHKLED--HTWHDLDTPSESN-ESTNPEAQSHAPCIAATQEIVSFIWPQVCL 171
                 |::.:|......:|  |:.||:.:..||: :|.:.....|.|   .|.|:.:...|
  Fly   129 AHVAPLMETVDFESLDFQDSSHSEHDIPSYWESSVDSGSLNTPHHQP---ETAELFAVEPP---- 186

  Fly   172 PLAVILSRITLGASLEEEVYVIEDESAKQDLGQEKLSISSKLLGARKRRGVRHTLE---CRICHR 233
                     |...|.||..   .|.:.|..:.:.:....:.....||..|..|...   |..|.:
  Fly   187 ---------TPPESSEEPA---PDAAEKPKMRRARPRQDNVKPKERKASGAVHPRSLHPCPECEK 239

  Fly   234 GFYKPSLLEAHMQQHEGL--RPYTCVHCAKSYARANLLESHLRQMHNNADAARIIYACPSCNKVY 296
            .|.:...|:.||....|:  ..|.|..|.|::|..:.|..|::.:|:....    :.|..|::.:
  Fly   240 KFTRNFQLKLHMTAVHGMGEMRYQCEECRKNFASRHSLRYHVKSVHSTERP----FGCQHCDRRF 300

  Fly   297 TANRSLKYHMRRTHERYHESESPDARHICEECGKCFARKAHLTRHKMVHGSVEGRRYCCECCDRR 361
            .....|..|:|.     |..|:......|:.|.|.:..|:.|..|...|.....|.:.|:.|.:.
  Fly   301 ILRTQLLSHLRT-----HTGEAKPRIFECQRCSKSWPTKSDLRTHMRSHNPNMERPFKCDRCSKA 360

  Fly   362 FYTKENMVDHLLRKHGNKNLLLRCRKCGRIFQNSVELNAH-GRKHKAMDVVQ 412
            |:|:.::..|||...|.|.  ..|..|.:.:|:...||.| .|.|  .|:::
  Fly   361 FFTRGHLNSHLLVHTGEKP--FACEYCDKCYQSVGNLNNHMVRLH--ADIIE 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071	25/133 (19%)
		C2H2 Zn finger	228..248	CDD:275368	6/19 (32%)
		C2H2 Zn finger	256..313	CDD:275368	12/56 (21%)
		C2H2 Zn finger	289..314	CDD:275368	5/24 (21%)
		zf-C2H2	323..345	CDD:278523	6/21 (29%)
		C2H2 Zn finger	325..345	CDD:275368	6/19 (32%)
		C2H2 Zn finger	355..376	CDD:275368	7/20 (35%)
		C2H2 Zn finger	385..405	CDD:275368	7/20 (35%)
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071	23/81 (28%)
		C2H2 Zn finger	234..255	CDD:275368	6/20 (30%)
		C2H2 Zn finger	264..285	CDD:275368	6/20 (30%)
		C2H2 Zn finger	293..313	CDD:275368	5/24 (21%)
		zf-C2H2_8	305..373	CDD:292531	19/72 (26%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	354..374	CDD:275368	7/19 (37%)
		zf-H2C2_2	366..389	CDD:290200	7/24 (29%)
		C2H2 Zn finger	382..403	CDD:275368	7/20 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100