DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10654 and ham

DIOPT Version :9

Sequence 1:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_724130.4	Gene:	ham / 35135	FlyBaseID:	FBgn0045852	Length:	1108	Species:	Drosophila melanogaster

Alignment Length:	179	Identity:	52/179 - (29%)
Similarity:	80/179 - (44%)	Gaps:	18/179 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 LECRICHRGFYKPSLLEAHM--QQHEGLRPYTCVHCAKSYARANLLESHLRQMHNNADAARIIYA 288
            :.|.:|.:.:....||:.|:  ..|.....:.|..||..:....||..|....|||...    |:
  Fly   339 IRCEVCDKVYPDLDLLDDHLIGAHHFKQDEFPCKQCALRFCHRPLLIKHEAISHNNIRK----YS 399

  Fly   289 CPSCNKVYTANRSLKYHMRRTHERYHESESPDAR-HICEECGKCFARKAHLTRHKMVHGSVEGRR 352
            |.:|:||:....:|:.|:|    .||..    || |.|.||||.|...:.|.:|:.:|.||  :.
  Fly   400 CENCSKVFCDPSNLQRHIR----AYHVG----ARCHPCPECGKTFGTSSGLKQHQHIHSSV--KP 454

  Fly   353 YCCECCDRRFYTKENMVDHLLRKHGNKNLLLRCRKCGRIFQNSVELNAH 401
            :.||.|.:.:....|:..| .|.|....:.::|.||.:.|.....|..|
  Fly   455 FACEVCSKAYTQFSNLCRH-KRMHATCRMQIKCDKCNQSFSTLTSLTKH 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071
		C2H2 Zn finger	228..248	CDD:275368	5/21 (24%)
		C2H2 Zn finger	256..313	CDD:275368	17/56 (30%)
		C2H2 Zn finger	289..314	CDD:275368	7/24 (29%)
		zf-C2H2	323..345	CDD:278523	9/21 (43%)
		C2H2 Zn finger	325..345	CDD:275368	8/19 (42%)
		C2H2 Zn finger	355..376	CDD:275368	6/20 (30%)
		C2H2 Zn finger	385..405	CDD:275368	6/17 (35%)
ham	NP_724130.4	PR-SET_ZFPM	131..253	CDD:380978
		C2H2 Zn finger	341..363	CDD:275368	5/21 (24%)
		C2H2 Zn finger	371..392	CDD:275368	6/20 (30%)
		SFP1	<391..479	CDD:227516	34/102 (33%)
		C2H2 Zn finger	400..421	CDD:275368	7/24 (29%)
		SUF4-like	403..>445	CDD:411020	18/49 (37%)
		C2H2 Zn finger	403..421	CDD:411020	6/21 (29%)
		C2H2 Zn finger	429..449	CDD:275368	8/19 (42%)
		C2H2 Zn finger	457..477	CDD:275368	6/20 (30%)
		C2H2 Zn finger	486..504	CDD:275368	6/17 (35%)
		PTZ00121	<641..>728	CDD:173412
		COG5048	935..>1028	CDD:227381
		zf-C2H2	935..957	CDD:395048
		C2H2 Zn finger	937..957	CDD:275368
		zf-H2C2_2	949..973	CDD:404364
		C2H2 Zn finger	965..986	CDD:275368
		C2H2 Zn finger	994..1014	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5270
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.860