DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10654 and Plzf

DIOPT Version :9

Sequence 1:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001285862.1	Gene:	Plzf / 34622	FlyBaseID:	FBgn0032401	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	78/393 - (19%)
Similarity:	145/393 - (36%)	Gaps:	89/393 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 DACHNLDSEQDLASKYYGCT--------------GEDAVRDLPPQLVLK--SICECCYQLVQKFH 99
            |....|||:..|:...:.|.              .:.::.: |.::.::  |..:|.:.:|..|:
  Fly    36 DLLLELDSDDSLSLSVHFCVLAAQSQFINSNQKQQQFSIHN-PLKITIRNFSCTQCLHTIVDFFY 99

  Fly   100 -DFQRMCAESLRNFEKLLQDIDI----GCHKL----EDHTWHDLDTPSESNESTNPEAQSHAPCI 155
             |...:..|...:|.:|.|.:.:    ..::|    |.....::..|.|:..:.:||.::.
  Fly   100 EDLVSVSKEHELHFRELAQILAVTELLNLYQLQPLGEAKEATEIPAPGEAQPNPDPEKKAE---- 160

  Fly   156 AATQEIVSFIWPQVCLPLAVILSRITLGASLEEEVYVIEDESAKQDLGQEKLSISSKLLGARKRR 220
                              ||..:|        :..:.:::..|.:...:....|.......:.::
  Fly   161 ------------------AVFENR--------QSYFKLKNPRAVKSSSKVNYCIGCDFKCYQVQK 199

  Fly   221 GVRHT-------LECRICHRGFYKPSLLEAHMQQHEG--LRPYTCVHCAKSY-ARANLLESHLRQ 275
            .:.|.       |.|.:|..||......:.|:::|.|  .:|:.|:.|...: .||.||
  Fly   200 MIEHMGSCEPSHLICSLCEVGFLDWREYDTHLRRHSGDLRKPFFCLQCGIRFNTRAALL------ 258

  Fly   276 MHNNADAARIIYACPSCNKVYTANRSLKYHMRRTHERYHESESPDARHICEECGKCFARKAHLTR 340
            :|....:....:.||.|.|.:...:.|..|: ..|       :|:.:.:|:.||........|..
  Fly   259 VHQPKHSTETPHICPHCGKGFKWKQGLSNHI-LVH-------NPEKQMLCDVCGYSTTHMKALKS 315

  Fly   341 HKMVHGSVEGRRYCCEC--CDRRFYTKENMVDHL-LRKHGNKNLLLRCRKCGRIFQNSVELNAHG 402
            ||::|   .|..:.|..  |..|...|||:..|: ..|.|...:   |..||..|..|..|..|.
  Fly   316 HKLLH---TGEFFACTVSGCKHRANRKENLKLHIETHKQGRDFI---CEVCGCKFSQSKNLKRHA 374

  Fly   403 RKH 405
            .||
  Fly   375 LKH 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071	14/80 (18%)
		C2H2 Zn finger	228..248	CDD:275368	5/19 (26%)
		C2H2 Zn finger	256..313	CDD:275368	14/57 (25%)
		C2H2 Zn finger	289..314	CDD:275368	7/24 (29%)
		zf-C2H2	323..345	CDD:278523	6/21 (29%)
		C2H2 Zn finger	325..345	CDD:275368	6/19 (32%)
		C2H2 Zn finger	355..376	CDD:275368	7/23 (30%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
Plzf	NP_001285862.1	COG5048	<193..403	CDD:227381	51/205 (25%)
		C2H2 Zn finger	214..234	CDD:275368	5/19 (26%)
		C2H2 Zn finger	244..264	CDD:275368	7/25 (28%)
		C2H2 Zn finger	272..292	CDD:275368	6/20 (30%)
		C2H2 Zn finger	300..320	CDD:275368	6/19 (32%)
		C2H2 Zn finger	330..349	CDD:275368	6/18 (33%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
		C2H2 Zn finger	387..408	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100