DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10654 and CG11695

DIOPT Version :9

Sequence 1:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_572732.1	Gene:	CG11695 / 32106	FlyBaseID:	FBgn0030316	Length:	544	Species:	Drosophila melanogaster

Alignment Length:	413	Identity:	103/413 - (24%)
Similarity:	159/413 - (38%)	Gaps:	85/413 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 MICRACLVLLGPQDACHNLD-SEQDLASKYYGCTGEDAVRD--------------LPPQLVLKSI 87
            ||||.||     .||.|::. .:||       .:|:..|..              ||...|.||:
  Fly     1 MICRLCL-----DDAEHSVPIFDQD-------DSGDQPVPSNLAELIEKHLQLVLLPNDGVSKSL 53

  Fly    88 CECCYQLVQKFHDFQRMCAESLRNFEKLLQ----------------------DIDIGCHKLEDHT 130
            |..|:   |:..||::.||..::....|.|                      :||:.....::..
  Fly    54 CTQCW---QQLADFEQFCAMVMKKQLGLQQLKMEPFSEDEDADTKAQILCEPEIDVSPAAADNEE 115

  Fly   131 WHDLDTPSESNESTNPEAQSHAPCIAAT----QEIVSFIWPQVCLPLAVILSRI-TLGASLEEEV 190
            .:::|..:.||        |.:..|..|    ..:.|.|..::.||.||...:. .:.|....:.
  Fly   116 CNEIDGDASSN--------SRSSSIRTTSLREMRLPSPIRRRMRLPRAVTAPKTQAVKAKARTKT 172

  Fly   191 Y---VIEDESAKQDLGQEKLSISSKLLGARKRRGVRHTLECRICHRGFYKPSLLE--AHMQQHEG 250
            :   ..|||.|:.:...|..|.:|:.:.:  ...:...|||.||......|:..|  .|.:.|..
  Fly   173 HKAEADEDEDAEGEGDPESRSSNSREMDS--YIALHGRLECCICGGDEQFPNFAEMKRHFRNHHQ 235

  Fly   251 LRPYTCVHCAKSYARANLLESHLRQMHNNADAARIIYACPSCNKVYTANRSLKYHMRRTHERYHE 315
            ...|. |.|.:.|.:..|...|| .|||:.:    .:.|..|:|...:..|...||.|.|
  Fly   236 SLGYV-VCCQRRYKKRALYVDHL-HMHNDPN----YFRCKICSKQLVSRISYDVHMLRFH----- 289

  Fly   316 SESPDARHICEECGKCFARKAHLTRHKMVHGSVEGRRYCCECCDRRFYTKENMVDHLLRKHGNKN 380
            ....|....|::|.|.|:::..||.|..||  .:.|...|:.|||.|.|..::..|:.|.|....
  Fly   290 PNKDDLSFACDQCSKRFSKQFLLTIHSRVH--QQERNEQCKHCDRSFRTAVDLRLHMRRTHDPAF 352

  Fly   381 LLLRCRKCGRIFQNSVELNAHGR 403
            :...|..||..|:....|..|.|
  Fly   353 VPFICDSCGAKFKTKQNLLVHKR 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071	24/90 (27%)
		C2H2 Zn finger	228..248	CDD:275368	6/21 (29%)
		C2H2 Zn finger	256..313	CDD:275368	17/56 (30%)
		C2H2 Zn finger	289..314	CDD:275368	8/24 (33%)
		zf-C2H2	323..345	CDD:278523	7/21 (33%)
		C2H2 Zn finger	325..345	CDD:275368	7/19 (37%)
		C2H2 Zn finger	355..376	CDD:275368	8/20 (40%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
CG11695	NP_572732.1	zf-AD	2..81	CDD:285071	25/93 (27%)
		C2H2 Zn finger	268..289	CDD:275368	7/20 (35%)
		C2H2 Zn finger	299..319	CDD:275368	7/19 (37%)
		C2H2 Zn finger	327..348	CDD:275368	8/20 (40%)
		C2H2 Zn finger	357..376	CDD:275368	7/19 (37%)
		C2H2 Zn finger	389..409	CDD:275368
		C2H2 Zn finger	420..440	CDD:275368
		C2H2 Zn finger	448..468	CDD:275368
		C2H2 Zn finger	476..494	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455495
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930