DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10654 and mld

DIOPT Version :9

Sequence 1:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001247289.1	Gene:	mld / 2768685	FlyBaseID:	FBgn0263490	Length:	1965	Species:	Drosophila melanogaster

Alignment Length:	188	Identity:	52/188 - (27%)
Similarity:	71/188 - (37%)	Gaps:	55/188 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 CRICHRGFYKPSLLEAHMQQH--EGLRPYTCVHCAKSYARANLLESHLRQMHNNADAARIIYACP 290
            |.||.||:...:.|..||:.|  || |||.|..|...:.|.:.|..|...:|        :.:.|
  Fly  1756 CTICKRGYRMRTALHRHMESHDVEG-RPYECNICRVRFPRPSQLTLHKITVH--------LLSKP 1811

  Fly   291 SCNKVYTANRSLKYHMRRTHERYHESESPDARHICEECGKCFARKAHLTRHKMVHGSVEGRRYCC 355
                                            |.|:||||.|..::.|..|...||.:   .|.|
  Fly  1812 --------------------------------HTCDECGKQFGTESALKTHIKFHGEL---GYQC 1841

  Fly   356 ECCDRRF-YTKENMVDHLLRKH--GNKNLLLRCRKCGRIFQNSVELNAHGRKHKAMDV 410
            :.|||.| |.||      ||||  .:..:..:|:.|...|.......||.:.|..:.|
  Fly  1842 DGCDRTFEYLKE------LRKHRRTHSEMFYKCKFCPSSFMRFTNFRAHMKTHLPLGV 1893

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071
		C2H2 Zn finger	228..248	CDD:275368	8/19 (42%)
		C2H2 Zn finger	256..313	CDD:275368	7/56 (13%)
		C2H2 Zn finger	289..314	CDD:275368	1/24 (4%)
		zf-C2H2	323..345	CDD:278523	9/21 (43%)
		C2H2 Zn finger	325..345	CDD:275368	8/19 (42%)
		C2H2 Zn finger	355..376	CDD:275368	10/21 (48%)
		C2H2 Zn finger	385..405	CDD:275368	5/19 (26%)
mld	NP_001247289.1	zf-AD	186..255	CDD:214871
		C2H2 Zn finger	1365..1388	CDD:275368
		C2H2 Zn finger	1396..1416	CDD:275368
		C2H2 Zn finger	1424..1445	CDD:275368
		C2H2 Zn finger	1725..1746	CDD:275368
		C2H2 Zn finger	1756..1776	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1785..1806	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1814..1834	CDD:275368	8/19 (42%)
		zf-C2H2	1839..1861	CDD:278523	13/27 (48%)
		C2H2 Zn finger	1841..1861	CDD:275368	12/25 (48%)
		C2H2 Zn finger	1868..1888	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439967
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840