DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10654 and ZNF324

DIOPT Version :9

Sequence 1:NP_001261767.1 Gene:CG10654 / 39428 FlyBaseID:FBgn0036294 Length:412 Species:Drosophila melanogaster
Sequence 2:XP_005258770.1 Gene:ZNF324 / 25799 HGNCID:14096 Length:558 Species:Homo sapiens


Alignment Length:226 Identity:71/226 - (31%)
Similarity:102/226 - (45%) Gaps:32/226 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   182 LGASLEEEVYVI--EDESAKQDLGQEKLSISSKLLGARKRRGVRHTLECRICHRGFYKPSLLEAH 244
            :||..:|...::  ::.|...:|| |.|....|            :.|||.|.:.|.|.|.|..|
Human   229 MGAVWQEPHRLLGGQEPSTWDELG-EALHAGEK------------SFECRACSKVFVKSSDLLKH 280

  Fly   245 MQQHEGLRPYTCVHCAKSYARANLLESHLRQMHNNADAARIIYACPSCNKVYTANRSLKYHMRRT 309
            ::.|.|.|||.|..|.|::::.    |||.| |....:....||||.|.|.:..:.||.     .
Human   281 LRTHTGERPYECAQCGKAFSQT----SHLTQ-HQRIHSGETPYACPVCGKAFRHSSSLV-----R 335

  Fly   310 HERYHESESPDARHICEECGKCFARKAHLTRHKMVHGSVEGRRYCCECCDRRFYTKENMVDHLLR 374
            |:|.|.:|.   ...|.||||.|:..::|::|:.:|..  ||.|.|..|.|||....:::.|...
Human   336 HQRIHTAEK---SFRCSECGKAFSHGSNLSQHRKIHAG--GRPYACAQCGRRFCRNSHLIQHERT 395

  Fly   375 KHGNKNLLLRCRKCGRIFQNSVELNAHGRKH 405
            ..|.|..:  |..||..|.....|..|.|.|
Human   396 HTGEKPFV--CALCGAAFSQGSSLFKHQRVH 424

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10654NP_001261767.1 zf-AD 39..115 CDD:285071
C2H2 Zn finger 228..248 CDD:275368 8/19 (42%)
C2H2 Zn finger 256..313 CDD:275368 17/56 (30%)
C2H2 Zn finger 289..314 CDD:275368 8/24 (33%)
zf-C2H2 323..345 CDD:278523 8/21 (38%)
C2H2 Zn finger 325..345 CDD:275368 8/19 (42%)
C2H2 Zn finger 355..376 CDD:275368 6/20 (30%)
C2H2 Zn finger 385..405 CDD:275368 7/19 (37%)
ZNF324XP_005258770.1 KRAB 6..66 CDD:214630
KRAB 6..45 CDD:279668
C2H2 Zn finger 264..284 CDD:275368 8/19 (42%)
COG5048 <268..468 CDD:227381 58/174 (33%)
zf-H2C2_2 276..301 CDD:290200 10/24 (42%)
C2H2 Zn finger 292..312 CDD:275368 8/24 (33%)
zf-H2C2_2 304..329 CDD:290200 10/25 (40%)
C2H2 Zn finger 320..340 CDD:275368 8/24 (33%)
zf-H2C2_2 332..357 CDD:290200 12/32 (38%)
C2H2 Zn finger 348..368 CDD:275368 8/19 (42%)
zf-C2H2 374..396 CDD:278523 7/21 (33%)
C2H2 Zn finger 376..396 CDD:275368 6/19 (32%)
zf-H2C2_2 388..413 CDD:290200 7/26 (27%)
C2H2 Zn finger 404..424 CDD:275368 7/19 (37%)
zf-H2C2_2 416..441 CDD:290200 4/9 (44%)
C2H2 Zn finger 432..452 CDD:275368
COG5048 437..>524 CDD:227381
zf-H2C2_2 444..468 CDD:290200
C2H2 Zn finger 460..480 CDD:275368
zf-H2C2_2 473..495 CDD:290200
C2H2 Zn finger 488..508 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.