DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10654 and Zfp160

DIOPT Version :10

Sequence 1:NP_001261767.1 Gene:CG10654 / 39428 FlyBaseID:FBgn0036294 Length:412 Species:Drosophila melanogaster
Sequence 2:NP_663458.2 Gene:Zfp160 / 224585 MGIID:108187 Length:650 Species:Mus musculus


Alignment Length:423 Identity:102/423 - (24%)
Similarity:152/423 - (35%) Gaps:111/423 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 GAKTMICRACLVLLGPQDACH-NLDSEQDL--ASKYYGCTGEDAVRDLPPQLVLKSICECCYQLV 95
            |.|...|..|    |...:.| ||::.|.:  ..|.|.|:                  ||.....
Mouse   282 GEKPYRCNEC----GKVFSSHSNLNTHQAIHTGEKPYKCS------------------ECGKVFT 324

  Fly    96 QKFH--DFQRM-----------CAESLRNFEKLLQDIDIGCHKLEDHTWHDLDTPSESNESTNPE 147
            |..|  :..|:           |.::...:..|.....|          |..:.|.:.||.....
Mouse   325 QNSHLANHWRIHTGEKPYKCNECGKAFSVYSSLTTHQAI----------HTGEKPYKCNECGKVF 379

  Fly   148 AQ-SHAPCIAATQEIVSFIWPQVCLPLAVILSRITLGASLEEEVYVIEDESAKQDLGQEKLSISS 211
            .| ||   :|:.:.:.|...|..|.....:.|: |...:....|:..|......:.| :..|:.|
Mouse   380 TQNSH---LASHRGVHSGEKPYKCEECGKLFSQ-TSNLARHWRVHTGEKPYKCSECG-KAFSVRS 439

  Fly   212 KLLGARKRRGVRHTLE----CRICHRGFYKPSLLEAHMQQHEGLRPYTCVHCAKSYARANLLESH 272
            .|:..:    |.||.|    |..|.:.|.:.|.|..|.:.|.|.:||.|..|.|::         
Mouse   440 SLIAHQ----VIHTGEKPYKCTECGKVFSQTSSLSIHQRIHTGEKPYRCNECGKAF--------- 491

  Fly   273 LRQMHNNADAARII------YACPSCNKVYTANRSLKYHMR-----------------------R 308
              ..|:|.:..::|      |.|..|.||:|.|..|..|.|                       .
Mouse   492 --NSHSNLNTHQVIHTGQKPYKCMQCGKVFTQNSHLANHQRTHTGEKPYKCNECGKAFSVYSSLT 554

  Fly   309 THERYHESESPDARHICEECGKCFARKAHLTRHKMVHGSVEGRR-YCCECCDRRFYTKENMVDHL 372
            ||:..|..|.|   :.|.||||.|.:.:||..|:..|   .|.: |.|..||:.|..:.::..|.
Mouse   555 THQAIHTGEKP---YKCNECGKVFTQNSHLASHRRTH---TGEKPYQCNKCDKAFSVRSSLTTHQ 613

  Fly   373 LRKHGNKNLLLRCRKCGRIFQNSVELNAHGRKH 405
            ....|.|.  ..|.:||::|..|..|.:|.|.|
Mouse   614 AIHTGEKP--YTCSECGKVFSRSSNLTSHQRLH 644

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10654NP_001261767.1 zf-AD 39..115 CDD:462262 16/91 (18%)
C2H2 Zn finger 228..248 CDD:275368 6/19 (32%)
SFP1 <243..310 CDD:227516 21/95 (22%)
C2H2 Zn finger 256..313 CDD:275368 18/85 (21%)
SFP1 <287..376 CDD:227516 32/112 (29%)
C2H2 Zn finger 289..314 CDD:275368 11/47 (23%)
C2H2 Zn finger 325..345 CDD:275368 9/19 (47%)
C2H2 Zn finger 355..376 CDD:275368 5/20 (25%)
C2H2 Zn finger 385..405 CDD:275368 8/19 (42%)
Zfp160NP_663458.2 KRAB 8..68 CDD:214630
C2H2 Zn finger 148..168 CDD:275368
C2H2 Zn finger 176..196 CDD:275368
COG5048 200..635 CDD:227381 97/412 (24%)
C2H2 Zn finger 204..224 CDD:275368
C2H2 Zn finger 232..252 CDD:275368
C2H2 Zn finger 260..280 CDD:275368
C2H2 Zn finger 288..308 CDD:275368 7/23 (30%)
C2H2 Zn finger 316..336 CDD:275368 6/37 (16%)
C2H2 Zn finger 344..364 CDD:275368 3/29 (10%)
C2H2 Zn finger 372..392 CDD:275368 6/22 (27%)
C2H2 Zn finger 400..420 CDD:275368 3/20 (15%)
C2H2 Zn finger 428..448 CDD:275368 5/24 (21%)
C2H2 Zn finger 456..476 CDD:275368 6/19 (32%)
C2H2 Zn finger 484..504 CDD:275368 5/30 (17%)
C2H2 Zn finger 512..532 CDD:275368 9/19 (47%)
C2H2 Zn finger 540..560 CDD:275368 2/19 (11%)
C2H2 Zn finger 568..588 CDD:275368 9/19 (47%)
C2H2 Zn finger 596..616 CDD:275368 5/19 (26%)
C2H2 Zn finger 624..644 CDD:275368 8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

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