DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10654 and ZNF497

DIOPT Version :9

Sequence 1:NP_001261767.1 Gene:CG10654 / 39428 FlyBaseID:FBgn0036294 Length:412 Species:Drosophila melanogaster
Sequence 2:NP_001193938.1 Gene:ZNF497 / 162968 HGNCID:23714 Length:498 Species:Homo sapiens


Alignment Length:213 Identity:59/213 - (27%)
Similarity:87/213 - (40%) Gaps:38/213 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   217 RKRRGVR-HTLECRICHRGFYKPSLLEAHMQQHEGLRPYTCVHCAKSYARANLLESHLRQMHNNA 280
            |...|.| |.  ||.|.:.|.:.|.|..|::.|.|.||:.|..|.|::.|...|..| |:.|::.
Human   238 RVHTGARPHA--CRDCGKAFSQSSNLAEHLKIHAGARPHACPDCGKAFVRVAGLRQH-RRTHSSE 299

  Fly   281 DAARIIYACPSCNKVYTANRSLKYHMR-----------------------RTHERYHESESPDAR 322
            ..    :.|..|.|.:..:..|..|.|                       ..|.|.|..|.|   
Human   300 KP----FPCAECGKAFRESSQLLQHQRTHTGERPFECAECGQAFVMGSYLAEHRRVHTGEKP--- 357

  Fly   323 HICEECGKCFARKAHLTRHKMVHGSVEGRRYCCECCDRRFYTKENMVDHLLRKHGNKNLLLRCRK 387
            |.|.:|||.|:::::|..|:..|..  .:.:.|..|.:.|.....:..|.|...|.:.  ..|.:
Human   358 HACAQCGKAFSQRSNLLSHRRTHSG--AKPFACADCGKAFRGSSGLAHHRLSHTGERP--FACAE 418

  Fly   388 CGRIFQNSVELNAHGRKH 405
            ||:.|:.|.||..|.|.|
Human   419 CGKAFRGSSELRQHQRLH 436

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10654NP_001261767.1 zf-AD 39..115 CDD:285071
C2H2 Zn finger 228..248 CDD:275368 7/19 (37%)
C2H2 Zn finger 256..313 CDD:275368 15/79 (19%)
C2H2 Zn finger 289..314 CDD:275368 8/47 (17%)
zf-C2H2 323..345 CDD:278523 8/21 (38%)
C2H2 Zn finger 325..345 CDD:275368 7/19 (37%)
C2H2 Zn finger 355..376 CDD:275368 5/20 (25%)
C2H2 Zn finger 385..405 CDD:275368 9/19 (47%)
ZNF497NP_001193938.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 30..104
COG5048 107..492 CDD:227381 59/213 (28%)
C2H2 Zn finger 108..128 CDD:275368
zf-H2C2_2 120..144 CDD:290200
C2H2 Zn finger 136..156 CDD:275368
zf-H2C2_2 148..171 CDD:290200
C2H2 Zn finger 164..184 CDD:275368
zf-C2H2 190..212 CDD:278523
C2H2 Zn finger 192..212 CDD:275368
zf-H2C2_2 205..228 CDD:290200
C2H2 Zn finger 220..240 CDD:275368 1/1 (100%)
C2H2 Zn finger 248..268 CDD:275368 7/19 (37%)
C2H2 Zn finger 276..296 CDD:275368 7/20 (35%)
zf-H2C2_2 289..311 CDD:290200 7/26 (27%)
C2H2 Zn finger 304..324 CDD:275368 6/19 (32%)
zf-H2C2_2 317..340 CDD:290200 3/22 (14%)
C2H2 Zn finger 332..352 CDD:275368 2/19 (11%)
zf-H2C2_2 344..369 CDD:290200 11/27 (41%)
C2H2 Zn finger 360..380 CDD:275368 7/19 (37%)
C2H2 Zn finger 388..408 CDD:275368 5/19 (26%)
C2H2 Zn finger 416..436 CDD:275368 9/19 (47%)
zf-H2C2_2 428..453 CDD:290200 5/9 (56%)
C2H2 Zn finger 444..464 CDD:275368
zf-H2C2_2 456..481 CDD:290200
C2H2 Zn finger 472..492 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165142281
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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