DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10681 and KXD1

DIOPT Version :9

Sequence 1:	NP_001261766.1	Gene:	CG10681 / 39425	FlyBaseID:	FBgn0036291	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001165419.1	Gene:	KXD1 / 79036	HGNCID:	28420	Length:	176	Species:	Homo sapiens

Alignment Length:	171	Identity:	70/171 - (40%)
Similarity:	93/171 - (54%)	Gaps:	14/171 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 NSAAEAFIQSLAGMVNQGDVETMIRAQKQMLQRFEKTNEMLLNCNALSQSRLKSASEDFKRHVKC 91
            :||:..|...:..|||..||..:|.|||.||.|||||||||||.|.||.:||:..||.|..|.:.
Human     5 DSASRVFCGRILSMVNTDDVNAIILAQKNMLDRFEKTNEMLLNFNNLSSARLQQMSERFLHHTRT 69

  Fly    92 LSEMKKDLDYIFRKIRIIKQKLQSQFPAIYAEVQPQRSSLAEEAEDD----------TEAQAKKT 146
            |.|||:|||.|||:||.:|.||..|.|..::.: |:.|.|.||.||.          |..|:..:
Human    70 LVEMKRDLDSIFRRIRTLKGKLARQHPEAFSHI-PEASFLEEEDEDPIPPSTTTTIATSEQSTGS 133

  Fly   147 AETPAPAAAKPVLSTKKSAATIEYVQMEEAVDNGTVEIENE 187
            .:| :|....|.||  .....:.:||......||..:.::|
Human   134 CDT-SPDTVSPSLS--PGFEDLSHVQPGSPAINGRSQTDDE 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10681	NP_001261766.1	KxDL	36..114	CDD:287243	45/77 (58%)
KXD1	NP_001165419.1	KxDL	14..93	CDD:287243	46/78 (59%)
KXD1	NP_001165419.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	95..176		20/81 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148262
Domainoid	1	1.000	92	1.000	Domainoid score	I7626
eggNOG	1	0.900	-	-		E1_KOG3443
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I4921
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1612645at2759
OrthoFinder	1	1.000	-	-		FOG0006436
OrthoInspector	1	1.000	-	-		oto90884
orthoMCL	1	0.900	-	-		OOG6_105852
Panther	1	1.100	-	-	LDO	PTHR13511
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4626
SonicParanoid	1	1.000	-	-		X4698
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790