Protein Alignment CG10638 and KCNAB3

DIOPT Version :10

• Sequence 1: NP_729808.1
• Gene: CG10638 / 39424
• FlyBaseID: FBgn0036290
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_047293000.1
• Gene: KCNAB3 / 9196
• HGNCID: 6230
• Length: 460
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 66/313 - (21%)
• Similarity: 106/313 - (33%)
• Gaps: 90/313 - (28%)

  Fly    11 NGYEMPILGLGTYNSKDNE-GEAAVKHAIDVGYRH----IDTAYFY---QNEAEVGKAIRDKIAE 67
            :|..:..|||||:.:..:: .:...:..:.|.|.|    .|||..|   :.|..:|..::.|
Human    86 SGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK--- 147

  Fly    68 GVVKREDIFLVTKL-WNIFHDPER-------VEGICRKQLSNFGLDYIDLYLMHMPVGYKYVDDN 124
             ..:|....:.||: |....:.||       :||: |..|....|.|:|:...:..      |.|
Human   148 -GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGL-RGSLERLQLGYVDIVFANRS------DPN 204

  Fly   125 TLLPKNEDDVLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVLANCE----IKPVTN 185
              .|..|             ..:||..::..||....|.|.:.:.::....:...    |.||..
Human   205 --CPMEE-------------IVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCE 254

  Fly   186 QVECS-----------PALNQK-----------ALTAFCKKND--------VTLTGYTPLGKPKP 220
            |.|..           |.|..|           |......|.|        .::.||..|   |.
Human   255 QAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITSKYDGRVPDTCRASIKGYQWL---KD 316

  Fly   221 DIQKPDFIYSP----EVAVIAKKYGKTTPQIVLRYLVGLGVIPI-PKSSNTNR 268
            .:|..|.....    ::..:|.:.|.|..|:      .:|..|. |..|:.||
Human   317 KVQSEDGKKQQAKVMDLLPVAHQLGCTVAQL------AIGAEPADPADSDGNR 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_729808.1	AKR_AKR2E1-5	5..298	CDD:381342	66/313 (21%)
KCNAB3	XP_047293000.1	AKR_SF	76..349	CDD:444925	60/297 (20%)