Protein Alignment CG10638 and AKR1C3

DIOPT Version :9

• Sequence 1: NP_001287050.1
• Gene: CG10638 / 39424
• FlyBaseID: FBgn0036290
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001240837.1
• Gene: AKR1C3 / 8644
• HGNCID: 386
• Length: 323
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 137/329 - (41%)
• Similarity: 184/329 - (55%)
• Gaps: 31/329 - (9%)

  Fly     7 VKLNNGYEMPILGLGTY------NSKDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKI 65
            :|||:|:.||:||.|||      .||..|   ..|.||:.|:||||:|:.|.||.:||.|||.||
Human     8 LKLNDGHFMPVLGFGTYAPPEVPRSKALE---VTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69

  Fly    66 AEGVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYVDDNTLLPKN 130
            |:|.|||||||..:|||:.||.||.|.......|....|||:||||:|.|:..|..::  |.|.:
Human    70 ADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE--LSPTD 132

  Fly   131 EDDVLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVL--ANCEIKPVTNQVECSPAL 193
            |:..:....||...|::||||....||.:||||||||..||..:|  ...:.|||.|||||.|..
Human   133 ENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYF 197

  Fly   194 NQKALTAFCKKNDVTLTGYTPLGKPKP----DIQKPDFIYSPEVAVIAKKYGKTTPQIVLRYLVG 254
            |:..|..|||..|:.|..|:.||..:.    |...|..:..|.:..:|||:.:|...|.|||.:.
Human   198 NRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQ 262

  Fly   255 LGVIPIPKSSNTNRISENFDIFDFELTAEEMAVLDG------YHTGERVVPLNLIKGLNHKYYPF 313
            .||:.:.||.|..||.:|..:|:|:||||:|..:||      |...:...        :|..||:
Human   263 RGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFA--------SHPNYPY 319

  Fly   314 SIEF 317
            |.|:
Human   320 SDEY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_001287050.1	ARA1	5..302	CDD:223729	132/312 (42%)
		Tas	5..297	CDD:223739	132/307 (43%)
AKR1C3	NP_001240837.1	ARA1	9..305	CDD:223729	131/300 (44%)
		Tas	17..297	CDD:223739	124/284 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730