Protein Alignment CG10638 and GCY1

DIOPT Version :10

• Sequence 1: NP_729808.1
• Gene: CG10638 / 39424
• FlyBaseID: FBgn0036290
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_014763.1
• Gene: GCY1 / 854287
• SGDID: S000005646
• Length: 312
• Species: Saccharomyces cerevisiae
• Alignment Length: 321
• Identity: 115/321 - (35%)
• Similarity: 171/321 - (53%)
• Gaps: 34/321 - (10%)

  Fly     7 VKLNNGYEMPILGLGTYNSKDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAEGVVK 71
            :.||.|.::|.:||||:.||:|:...||..|:..||||||||..|:||.:||:||:|    ..|.
Yeast    12 LSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKD----SGVP 72

  Fly    72 REDIFLVTKLW-NIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPV----GYKYVDDNTLLPKNE 131
            ||:||:.|||| ...|:||..   ..:.|...||||:||||||.|.    .|...:|...:|..:
Yeast    73 REEIFVTTKLWCTQHHEPEVA---LDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKK 134

  Fly   132 DD--VLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVLAN--CEIKPVTNQVECSPA 192
            |.  .:.:::.:::.|::.|::|.|.|..:::|||||:...|..:||:  .::.|..||||..|.
Yeast   135 DGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPL 199

  Fly   193 LNQKALTAFCKKNDVTLTGYTPLGKPKPDIQKPDFIYSPEVAVIAKKYGKTTPQIVLRYLVGLGV 257
            |.|..|..|||...:.:..|:|||.....:.|     .|.:..||||.......:|:.:.|..|.
Yeast   200 LPQDELINFCKSKGIVVEAYSPLGSTDAPLLK-----EPVILEIAKKNNVQPGHVVISWHVQRGY 259

  Fly   258 IPIPKSSNTNRISENFDIFDFELTAEEMAVLDGY--HTGE-RVVPLNLIKGLNHKYYPFSI 315
            :.:|||.|.:||..|..|  |.|:.|:...::..  ..|| |||..|        :.||.:
Yeast   260 VVLPKSVNPDRIKTNRKI--FTLSTEDFEAINNISKEKGEKRVVHPN--------WSPFEV 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_729808.1	AKR_AKR2E1-5	5..298	CDD:381342	110/302 (36%)
GCY1	NP_014763.1	AKR_AKR3A1-2	7..296	CDD:381343	107/297 (36%)