Protein Alignment CG10638 and AKR1E2

DIOPT Version :9

• Sequence 1: NP_001287050.1
• Gene: CG10638 / 39424
• FlyBaseID: FBgn0036290
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_011518017.1
• Gene: AKR1E2 / 83592
• HGNCID: 23437
• Length: 341
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 140/307 - (45%)
• Similarity: 182/307 - (59%)
• Gaps: 30/307 - (9%)

  Fly    33 AVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAEGVVKREDIFLVTKLWNIFHDPERVEGICRK 97
            |||.|||.||||.|.||||.||.|||..||.||.||.|:|||:|:.||||...|....||..|||
Human    43 AVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRK 107

  Fly    98 QLSNFGLDYIDLYLMHMPVGYK--------------------YVDDNTLLPKNEDDVLQLSDVDY 142
            .|....|:|:||||:|.|:|:|                    .|.|   ||.:|.:::..||.|:
Human   108 SLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQD---LPLDESNMVIPSDTDF 169

  Fly   143 LDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVL--ANCEIKPVTNQVECSPALNQKALTAFCKKN 205
            |||::|||.||..|||::|||||||.|||.|:|  .....||:|||:||.|.|.||.|.:||:..
Human   170 LDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSR 234

  Fly   206 DVTLTGYTPLGKPKPDIQKPDFIYSPEVAVIAKKYGKTTPQIVLRYLVGLGVIPIPKSSNTNRIS 270
            ||::|.|.|||   ...:..|.|.:|.:..|||::||:..||::|:.:...||.||.|...:.|.
Human   235 DVSVTAYRPLG---GSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIK 296

  Fly   271 ENFDIFDFELTAEEMAVLDGYHTGERVVPLNLIKGLNHKYYPFSIEF 317
            ||..:||||||..:|..:...:...|:....:.|  |||.|||.||:
Human   297 ENIQVFDFELTQHDMDNILSLNRNLRLAMFPITK--NHKDYPFHIEY 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_001287050.1	ARA1	5..302	CDD:223729	131/290 (45%)
		Tas	5..297	CDD:223739	130/285 (46%)
AKR1E2	XP_011518017.1	ARA1	34..322	CDD:223729	130/284 (46%)
		Tas	42..314	CDD:223739	130/276 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.730