Protein Alignment CG10638 and AKR1D1

DIOPT Version :10

• Sequence 1: NP_729808.1
• Gene: CG10638 / 39424
• FlyBaseID: FBgn0036290
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_005980.1
• Gene: AKR1D1 / 6718
• HGNCID: 388
• Length: 326
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 138/321 - (42%)
• Similarity: 191/321 - (59%)
• Gaps: 14/321 - (4%)

  Fly     7 VKLNNGYEMPILGLGTYNSKDNEGEAA----VKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAE 67
            :.|::|..:||:|||||:...:..:.|    ||.|||.||||||.||.||||.|||:|||:||||
Human    10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAE 74

  Fly    68 GVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYVDDNTLLPKNED 132
            |.|:|||||...|||...|.||.|.....:.|....|||:|||::.:|:.:|..|:  :.|::|:
Human    75 GKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDE--IYPRDEN 137

  Fly   133 DVLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVL--ANCEIKPVTNQVECSPALNQ 195
            ........:...|::|||.....|||:|:||||||..||..:|  ...:.|||:|||||.|...|
Human   138 GKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQ 202

  Fly   196 KALTAFCKKNDVTLTGYTPLGKPK----PDIQKPDFIYSPEVAVIAKKYGKTTPQIVLRYLVGLG 256
            ..|..||:::|:.:|.|:|||..:    .::..|..:....:..:.|:|.||..|||||:.:..|
Human   203 PKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRG 267

  Fly   257 VIPIPKSSNTNRISENFDIFDFELTAEEMAVLDGYHTGERVVPLNLIKGLNHKYYPFSIEF 317
            |:.||||.|..||.|||.||||.||.|||..::..:...|.|  .|:...:|..|||..|:
Human   268 VVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFV--ELLMWRDHPEYPFHDEY 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_729808.1	AKR_AKR2E1-5	5..298	CDD:381342	131/300 (44%)
AKR1D1	NP_005980.1	AKR_AKR1D1-3	15..322	CDD:381335	134/310 (43%)