Protein Alignment CG10638 and AKR1B10

DIOPT Version :10

• Sequence 1: NP_729808.1
• Gene: CG10638 / 39424
• FlyBaseID: FBgn0036290
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_064695.3
• Gene: AKR1B10 / 57016
• HGNCID: 382
• Length: 316
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 138/322 - (42%)
• Similarity: 200/322 - (62%)
• Gaps: 13/322 - (4%)

  Fly     3 LAPTVKLNNGYEMPILGLGTYNSKDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAE 67
            :|..|:|:...:|||:||||:.|...:.:.|||.|||.||||||.||.||||.|||:||::||.|
Human     1 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65

  Fly    68 GVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYVDDNTLLPKNED 132
            ..|||||:|:|:|||..|.:...|.....|.|.:..|.|:|:||:|.|.|:|..||  |.||::.
Human    66 KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD--LFPKDDK 128

  Fly   133 DVLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVL--ANCEIKPVTNQVECSPALNQ 195
            .........:||.::|||:||..|||:::|||||:..|:.::|  ...:.|||||||||.|.|.|
Human   129 GNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQ 193

  Fly   196 KALTAFCKKNDVTLTGYTPLGKP-----KPDIQKPDFIYSPEVAVIAKKYGKTTPQIVLRYLVGL 255
            :.|..:|....:|:|.|:|||.|     ||  :.|..:..|::..||.|:.||..|:::|:.:..
Human   194 EKLIQYCHSKGITVTAYSPLGSPDRPWAKP--EDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQR 256

  Fly   256 GVIPIPKSSNTNRISENFDIFDFELTAEEMAVLDGYHTGERVVPLNLIKGLNHKYYPFSIEF 317
            .||.||||....||.||..:|||:|:.||||.:..::...|.  .|:::..:.:.|||:.|:
Human   257 NVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA--CNVLQSSHLEDYPFNAEY 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_729808.1	AKR_AKR2E1-5	5..298	CDD:381342	132/299 (44%)
AKR1B10	NP_064695.3	AKR_AKR1B1-19	10..316	CDD:381333	134/311 (43%)