Protein Alignment CG10638 and akr1c8

DIOPT Version :10

• Sequence 1: NP_729808.1
• Gene: CG10638 / 39424
• FlyBaseID: FBgn0036290
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001004955.1
• Gene: akr1c8 / 448368
• XenbaseID: XB-GENE-5757727
• Length: 324
• Species: Xenopus tropicalis
• Alignment Length: 322
• Identity: 143/322 - (44%)
• Similarity: 192/322 - (59%)
• Gaps: 17/322 - (5%)

  Fly     7 VKLNNGYEMPILGLGTYNSK---DNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAEG 68
            ::||:|::||:||.|||..:   .:..|...|.||||||||||:|:||.||.|||:|||.|||:|
 Frog     9 IELNDGHKMPVLGFGTYAPQKFPKSLAEEGTKVAIDVGYRHIDSAFFYGNEVEVGRAIRAKIADG 73

  Fly    69 VVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYVDDNTLLPKNEDD 133
            .|||||:|...|||:.||.||||.....|.|::..|||:||:::|:||..|..||.  ||.:|:.
 Frog    74 TVKREDVFYTGKLWSTFHTPERVRPALEKSLNDLQLDYMDLFIIHIPVELKPGDDP--LPLDENG 136

  Fly   134 VLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVL--ANCEIKPVTNQVECSPALNQK 196
            .....:.|..||:||:||....||||||||||||.:||..:|  ...:.|||.|||||...|||.
 Frog   137 KFIYHNTDIRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCNQVECHVYLNQS 201

  Fly   197 ALTAFCKKNDVTLTGYTPLGKPKP----DIQKPDFIYSPEVAVIAKKYGKTTPQIVLRYLVGLGV 257
            .|..|||..|:.|..:..||..:.    |...|..:..|.:..||||:..|..|:.:|||:..||
 Frog   202 KLLEFCKSKDIVLVAFGVLGSSRDESWIDPNLPVLLEDPVLNAIAKKHNCTPAQVAMRYLLQRGV 266

  Fly   258 IPIPKSSNTNRISENFDIFDFELTAEEMAVLDGYHTGER--VVPLNLIKGLNHKYYPFSIEF 317
            :.:.||....||.:||.:|:..|.||:|..:||.:...|  ..|:    ..:|..|||..|:
 Frog   267 VVLVKSFTPARIQQNFQVFNVHLDAEDMRNVDGINRNLRYDYAPM----WSDHPKYPFHEEY 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_729808.1	AKR_AKR2E1-5	5..298	CDD:381342	137/301 (46%)
akr1c8	NP_001004955.1	AKR_AKR1C1-35	8..306	CDD:381334	136/298 (46%)