Protein Alignment CG10638 and AKR1B15

DIOPT Version :9

• Sequence 1: NP_001287050.1
• Gene: CG10638 / 39424
• FlyBaseID: FBgn0036290
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001074007.2
• Gene: AKR1B15 / 441282
• HGNCID: 37281
• Length: 344
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 131/349 - (37%)
• Similarity: 191/349 - (54%)
• Gaps: 39/349 - (11%)

  Fly     1 MKLAPTVKLNNGYEM--------PILGLGTYNSKDNEG----------------EAAVKHAIDVG 41
            :::.|.|...|.:..        |:.||.:...||...                :.|||.|||..
Human     3 LQMEPQVNSTNNFHQGPLDQPVGPLTGLKSSLLKDTTSAGPLLRPYPASLLGKVKEAVKVAIDAE 67

  Fly    42 YRHIDTAYFYQNEAEVGKAIRDKIAEGVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDY 106
            |||||.||||:|:.|||:||::||.|..|.|||:|:|:|:|..|.:...|.....|.|.:..|.|
Human    68 YRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSY 132

  Fly   107 IDLYLMHMPVGYKYVDDNTLLPKNEDDVLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQL 171
            :|:||:|.|.|:|..||  ..||::...:......:||.::|||:||..|||:::||||||..|:
Human   133 LDVYLIHWPQGFKTGDD--FFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQI 195

  Fly   172 ARVL--ANCEIKPVTNQVECSPALNQKALTAFCKKNDVTLTGYTPLGKP-----KPDIQKPDFIY 229
            .|:|  ...:.|||||||||.|.|.|:.|..:|....:|:|.|:|||.|     ||  :.|..:.
Human   196 ERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKP--EDPSLLE 258

  Fly   230 SPEVAVIAKKYGKTTPQIVLRYLVGLGVIPIPKSSNTNRISENFDIFDFELTAEEMAVLDGYHTG 294
            .|::..||.|:.|||.|:::|:.:...|..||||.....|.||..:|||:|:.||||.:..::..
Human   259 DPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRN 323

  Fly   295 ERVVPLNLIKGLNH-KYYPFSIEF 317
            .|...   .|..:| :.:||..|:
Human   324 WRAFD---FKEFSHLEDFPFDAEY 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_001287050.1	ARA1	5..302	CDD:223729	126/327 (39%)
		Tas	5..297	CDD:223739	125/322 (39%)
AKR1B15	NP_001074007.2	ARA1	56..325	CDD:223729	117/272 (43%)
		Tas	57..317	CDD:223739	117/263 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158435
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.760