Protein Alignment CG10638 and Akr1c19

DIOPT Version :10

• Sequence 1: NP_729808.1
• Gene: CG10638 / 39424
• FlyBaseID: FBgn0036290
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001013807.2
• Gene: Akr1c19 / 432720
• MGIID: 2653678
• Length: 323
• Species: Mus musculus
• Alignment Length: 320
• Identity: 147/320 - (45%)
• Similarity: 188/320 - (58%)
• Gaps: 13/320 - (4%)

  Fly     7 VKLNNGYEMPILGLGTYNSKD-NEGE--AAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAEG 68
            ||||:|..:|.||.|||..:: ||.:  .|:..|::.|:|||||||.||.|..||:|||.|||.|
Mouse     8 VKLNDGNFIPALGFGTYKPEEVNENKPLEAIHLALEAGFRHIDTAYVYQTENHVGQAIRSKIAAG 72

  Fly    69 VVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYVDDNTLLPKNEDD 133
            :||||||||.||||..||.||.|.....|.|.|..|||.||||:|.||..|..:|  |.|::|..
Mouse    73 LVKREDIFLTTKLWCTFHRPELVRSNLEKSLKNLQLDYADLYLIHYPVQMKPGED--LFPEDEHG 135

  Fly   134 VLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVL--ANCEIKPVTNQVECSPALNQK 196
            ......||...|::||||....|||:|||||||||.||.::|  ...:.|||.|||||...|||:
Mouse   136 KTLFDTVDICATWEAMEKCKDAGLVKSIGVSNFNSRQLEKILNKPGLKYKPVCNQVECHLYLNQR 200

  Fly   197 ALTAFCKKNDVTLTGYTPLGKPKP----DIQKPDFIYSPEVAVIAKKYGKTTPQIVLRYLVGLGV 257
            .|..:||..|:.|..|..||..:|    |...|..:..|.:..:|||:.::..||.|||.:..|:
Mouse   201 KLLNYCKSKDIVLVAYCALGSQRPKRWVDPSSPVLLNDPILCDMAKKHKRSPAQIALRYHLQRGI 265

  Fly   258 IPIPKSSNTNRISENFDIFDFELTAEEMAVLDGYHTGERVVPLNLIKGLNHKYYPFSIEF 317
            :.:.:|...|.|.||..:|:|||.:|:|.:||......|..|...  |..|..||||.||
Mouse   266 VVLAQSYKENEIKENIQVFEFELPSEDMKILDSLDRNLRYAPAPF--GEGHPEYPFSDEF 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_729808.1	AKR_AKR2E1-5	5..298	CDD:381342	138/299 (46%)
Akr1c19	NP_001013807.2	AKR_AKR1C1-35	6..308	CDD:381334	138/301 (46%)