DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10638 and Y39G8B.1

DIOPT Version :9

Sequence 1:	NP_001287050.1	Gene:	CG10638 / 39424	FlyBaseID:	FBgn0036290	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001370070.1	Gene:	Y39G8B.1 / 175047	WormBaseID:	WBGene00012722	Length:	316	Species:	Caenorhabditis elegans

Alignment Length:	319	Identity:	140/319 - (43%)
Similarity:	196/319 - (61%)	Gaps:	7/319 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LAPTVKLNNGYEMPILGLGTYNSKDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAE 67
            :..::|||:||.:|.:||||:.||..|..||:|.|:..||||||.|:.|||:.|||:|:::.:.|
Worm     1 MVQSLKLNSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDE 65

  Fly    68 GVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYVDDNTLLPKNED 132
            |.||||::|:.:|:||.||...:........||:..|.|:||.|:|.|.|  |.:...|.|..|:
Worm    66 GKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQG--YAEGAELFPAGEN 128

  Fly   133 DVLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVLANCEIKPVTNQVECSPALNQKA 197
            ..::.||||||:|:||.|...|.|..||||:|||...|:.||....|:||...|||..|...|..
Worm   129 GKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVELHPYFTQVK 193

  Fly   198 LTAFCKKNDVTLTGYTPLGKPKPDIQK----PDFIYSPEVAVIAKKYGKTTPQIVLRYLVGLGVI 258
            |..|||:..:.:.||:|||.|.....:    |:.:.:..||.|||.:|||..||:||:.|..|:.
Worm   194 LREFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTNEVVAGIAKAHGKTPAQIILRWFVDSGLS 258

  Fly   259 PIPKSSNTNRISENFDIFDFELTAEEMAVLDGYHTGERVVPLNLIKGLNHKYYPFSIEF 317
            .||||....|||||..:|||:|||||::.:||.:...|:|.|:...| :|.:.||..||
Worm   259 AIPKSVTPQRISENLAVFDFQLTAEEISKIDGINKNWRIVDLSQRDG-DHPHCPFLEEF 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_001287050.1	ARA1	5..302	CDD:223729	134/300 (45%)
CG10638	NP_001287050.1	Tas	5..297	CDD:223739	131/295 (44%)
Y39G8B.1	NP_001370070.1	AKR_SF	7..305	CDD:412396	133/299 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166080
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		mtm8417
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.760