Protein Alignment CG10638 and AKR1C1

DIOPT Version :9

• Sequence 1: NP_001287050.1
• Gene: CG10638 / 39424
• FlyBaseID: FBgn0036290
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001344.2
• Gene: AKR1C1 / 1645
• HGNCID: 384
• Length: 323
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 143/323 - (44%)
• Similarity: 193/323 - (59%)
• Gaps: 19/323 - (5%)

  Fly     7 VKLNNGYEMPILGLGTY------NSKDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKI 65
            ||||:|:.||:||.|||      .||..|   |.|.||:.|:||||:|:.|.||.:||.|||.||
Human     8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE---ATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69

  Fly    66 AEGVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYVDDNTLLPKN 130
            |:|.|||||||..:|||...|.||.|.....:.|.|..|||:||||:|.||..|..::  ::||:
Human    70 ADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE--VIPKD 132

  Fly   131 EDDVLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVL--ANCEIKPVTNQVECSPAL 193
            |:..:....||...|::|:||....||.:||||||||..||..:|  ...:.|||.|||||.|..
Human   133 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYF 197

  Fly   194 NQKALTAFCKKNDVTLTGYTPLG----KPKPDIQKPDFIYSPEVAVIAKKYGKTTPQIVLRYLVG 254
            ||:.|..|||..|:.|..|:.||    :|..|...|..:..|.:..:|||:.:|...|.|||.:.
Human   198 NQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQ 262

  Fly   255 LGVIPIPKSSNTNRISENFDIFDFELTAEEMAVLDGYHTGERVVPLNLIKGLNHKYYPFSIEF 317
            .||:.:.||.|..||.:|..:|:|:||:|||..:||.:...|.:.|::..|..:  ||||.|:
Human   263 RGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPN--YPFSDEY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_001287050.1	ARA1	5..302	CDD:223729	137/306 (45%)
		Tas	5..297	CDD:223739	135/301 (45%)
AKR1C1	NP_001344.2	AKR_AKR1C1-35	6..308	CDD:381334	136/304 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730