Protein Alignment CG10638 and Akr1b8

DIOPT Version :10

• Sequence 1: NP_729808.1
• Gene: CG10638 / 39424
• FlyBaseID: FBgn0036290
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_032038.1
• Gene: Akr1b8 / 14187
• MGIID: 107673
• Length: 316
• Species: Mus musculus
• Alignment Length: 322
• Identity: 133/322 - (41%)
• Similarity: 202/322 - (62%)
• Gaps: 13/322 - (4%)

  Fly     3 LAPTVKLNNGYEMPILGLGTYNSKDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAE 67
            :|..|:|:...:|||:||||:.|..|:.:.|||.|||.||||||.||.|.||.|||:||::||.|
Mouse     1 MATFVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKE 65

  Fly    68 GVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYVDDNTLLPKNED 132
            ..|:|||:|:|:|||....:.:.::...:|.|::..|||:||||:|.|.|.:  ....|.||::.
Mouse    66 KAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQ--PGKELFPKDDQ 128

  Fly   133 DVLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVL--ANCEIKPVTNQVECSPALNQ 195
            ..:..|...:|:.::.||:||..|||:::||||||..|:.|:|  ...:.|||||||||.|.|.|
Mouse   129 GRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQ 193

  Fly   196 KALTAFCKKNDVTLTGYTPLGKP-----KPDIQKPDFIYSPEVAVIAKKYGKTTPQIVLRYLVGL 255
            :.|..:|....:::|.|:|||.|     ||  :.|..:..|::..||.|:.||:.|:::|:.:..
Mouse   194 EKLIQYCHSKGISVTAYSPLGSPDRPSAKP--EDPSLLEDPKIKEIAAKHEKTSAQVLIRFHIQR 256

  Fly   256 GVIPIPKSSNTNRISENFDIFDFELTAEEMAVLDGYHTGERVVPLNLIKGLNHKYYPFSIEF 317
            .|:.||||...:||.||..:|||:|:.||||.:..::...|...|.  :.:|.:.||:..|:
Mouse   257 NVVVIPKSVTPSRIQENIQVFDFQLSDEEMATILSFNRNWRACLLP--ETVNMEEYPYDAEY 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_729808.1	AKR_AKR2E1-5	5..298	CDD:381342	127/299 (42%)
Akr1b8	NP_032038.1	AKR_AKR1B1-19	10..316	CDD:381333	129/311 (41%)