Protein Alignment CG10638 and AKR1A1

DIOPT Version :9

• Sequence 1: NP_001287050.1
• Gene: CG10638 / 39424
• FlyBaseID: FBgn0036290
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001189342.1
• Gene: AKR1A1 / 10327
• HGNCID: 380
• Length: 325
• Species: Homo sapiens
• Alignment Length: 324
• Identity: 133/324 - (41%)
• Similarity: 195/324 - (60%)
• Gaps: 17/324 - (5%)

  Fly     4 APTVKLNNGYEMPILGLGTYNSKDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAEG 68
            |..|.|:.|.:||::||||:.|:..:.:||||:|:.|||||||.|..|.||.|:|:|:::.:..|
Human     3 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67

  Fly    69 -VVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYVDDNTLLPKNED 132
             .|.||::|:.:||||..|.||.||...||.|::..|:|:||||||.|..::..|:.  .|||.|
Human    68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNP--FPKNAD 130

  Fly   133 DVLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVLANCEIKPVTNQVECSPALNQKA 197
            ..:......|.:|:||:|.||..|||:::|:|||||.|:..:|:...::|...||||.|.|.|..
Human   131 GTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNE 195

  Fly   198 LTAFCKKNDVTLTGYTPLGKP-----KPDIQKPDFIYSPEVAVIAKKYGKTTPQIVLRYLVGLGV 257
            |.|.|:...:.:|.|:|||..     .||  :|..:..|.|..:|:|||::..||:||:.|...|
Human   196 LIAHCQARGLEVTAYSPLGSSDRAWRDPD--EPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKV 258

  Fly   258 IPIPKSSNTNRISENFDIFDFELTAEEMAVLDGYHTGER-VVPLNLIKG------LNHKYYPFS 314
            |.||||...:||.:|..:|||..:.|||..|:..:...| :||:..:.|      ..|..|||:
Human   259 ICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFN 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10638	NP_001287050.1	ARA1	5..302	CDD:223729	127/303 (42%)
		Tas	5..297	CDD:223739	125/298 (42%)
AKR1A1	NP_001189342.1	ARA1	6..303	CDD:223729	127/300 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.690