DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10657 and SFH5

DIOPT Version :9

Sequence 1:	NP_648579.3	Gene:	CG10657 / 39423	FlyBaseID:	FBgn0036289	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_012390.1	Gene:	SFH5 / 853296	SGDID:	S000003681	Length:	294	Species:	Saccharomyces cerevisiae

Alignment Length:	161	Identity:	30/161 - (18%)
Similarity:	59/161 - (36%)	Gaps:	40/161 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 RQVIFSVAAKFDPYKFTSVQMARVHSLVCEALLDDEDSQVAGYVYINDESGMNMGFVSLWSL-TD 202
            ::.:|....||..|:...::...       :|||...|.......::|..|     ||:|.: :|
Yeast   134 KKELFQNVDKFVRYRIGLMEKGL-------SLLDFTSSDNNYMTQVHDYKG-----VSVWRMDSD 186

  Fly   203 LRSIVKCI----QNSTPMRHKETHFVNIPHYANRIIELGVSMLSDKLKKRIIV------------ 251
            :::..|.:    |...|......:|||:|.....:.:|....:.:..:|:.:|
Yeast   187 IKNCSKTVIGIFQKYYPELLYAKYFVNVPTVFGWVYDLIKKFVDETTRKKFVVLTDGSKLGQYLK 251

  Fly   252 ----------HKNVDILKTKIDPAILPKEYG 272
                      .|..::.|..: ..:.|.|||
Yeast   252 DCPYEGYGGKDKKNNLTKQNV-TNVHPTEYG 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10657	NP_648579.3	CRAL_TRIO_N	52..98	CDD:215024
CG10657	NP_648579.3	CRAL_TRIO	126..274	CDD:279044	30/161 (19%)
SFH5	NP_012390.1	SEC14	101..263	CDD:214706	24/140 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900