Protein Alignment CG10657 and TTPAL

DIOPT Version :10

• Sequence 1: NP_648579.3
• Gene: CG10657 / 39423
• FlyBaseID: FBgn0036289
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_077307.2
• Gene: TTPAL / 79183
• HGNCID: 16114
• Length: 342
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 83/297 - (27%)
• Similarity: 140/297 - (47%)
• Gaps: 20/297 - (6%)

  Fly    13 SGPAASSGGDYDYP-------YVCGLSPAMKLVAKEELHEDENIRRQALAQFREWIEK-HPHIRK 69
            :.|:.:|..:.:.|       |||.|:..:...|:|||.|....|.:.:...|:.:.| :|:: .
Human    10 TSPSVASLSENELPPPPEPPGYVCSLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPNL-S 73

  Fly    70 CRTDTVFLLRFLRTKKFSVPSACEMLERYLTIRQLFPQWFKQLDINDPAINEIFENGYLVPLPQR 134
            ...|..|||||||.:||....|.::|..|.:.|:.:|:.|..|  ...|:.::..:|:|..||..
Human    74 TSLDDAFLLRFLRARKFDYDRALQLLVNYHSCRRSWPEVFNNL--KPSALKDVLASGFLTVLPHT 136

  Fly   135 DSTGRQVIFSVAAKFDPYKFTSVQMARVHSLVCEALLDDEDSQVAGYVYINDESGMNMGFVSLWS 199
            |..|..|:.....::.|..:...:..|...|..|.|:..|::||.|.|.:.|..|:::...|.:.
Human   137 DPRGCHVVCIRPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG 201

  Fly   200 LTDLRSIVKCIQNSTPMRHKETHFVNIPHYANRIIELGVSMLSDKLKKRIIVH-KNVDILKTKID 263
            ....:.::..:|:..|:|.|..|.||.|.....|..:....|.:|:..|..:| .:::.|.|.:.
Human   202 PFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP 266

  Fly   264 PAILPKEYGGTVPIADMIAQFKQKLQQRRAAILALDD 300
            .:|||||||||....|....        .|.:||.:|
Human   267 RSILPKEYGGTAGELDTATW--------NAVLLASED 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10657	NP_648579.3	CRAL_TRIO_N	52..98	CDD:215024	15/46 (33%)
		CRAL_TRIO	126..273	CDD:459890	41/147 (28%)
TTPAL	NP_077307.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		3/20 (15%)
		CRAL_TRIO_N	56..102	CDD:215024	15/46 (33%)
		SEC14	128..277	CDD:469559	42/148 (28%)