Protein Alignment CG10657 and TTPA

DIOPT Version :10

• Sequence 1: NP_648579.3
• Gene: CG10657 / 39423
• FlyBaseID: FBgn0036289
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_001400347.1
• Gene: TTPA / 7274
• HGNCID: 12404
• Length: 317
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 62/243 - (25%)
• Similarity: 105/243 - (43%)
• Gaps: 45/243 - (18%)

  Fly    72 TDTVFLLRFLRTKKFSVPSACEMLERYLTIRQLFPQWFKQLDINDPAINEIFENGYLVPLPQRDS 136
            ||: |||||||.:.|.:..|..:|:.|...|...|:  ...|::..:|..:.:.||...|..||.
Human    48 TDS-FLLRFLRARDFDLDLAWRLLKNYYKWRAECPE--ISADLHPRSIIGLLKAGYHGVLRSRDP 109

  Fly   137 TGRQVIF------SVA---------------------------------AKFDPYKFTSVQMARV 162
            ||.:|:.      |||                                 |.:||..||:..:.||
Human   110 TGSKVLIYRIESCSVAQAGEQWAISTHYNLCLPSSSDSPASASQVAGTTAHWDPKVFTAYDVFRV 174

  Fly   163 HSLVCEALLDDEDSQVAGYVYINDESGMNMGFVSLWSLTDLRSIVKCIQNSTPMRHKETHFVNIP 227
            ..:..|.::.:.::|..|...|.|..|.........:.:..:.|...:.:|.|::.:..|.:|.|
Human   175 SLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEP 239

  Fly   228 HYANRIIELGVSMLSDKLKKRIIVHKNVDILKTKID--PAILPKEYGG 273
            ...:.:..:....|::|:|:||.:|.| :..::.:.  |.|||.||||
Human   240 VIFHAVFSMIKPFLTEKIKERIHMHGN-NYKQSLLQHFPDILPLEYGG 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10657	NP_648579.3	CRAL_TRIO_N	52..98	CDD:215024	12/25 (48%)
		CRAL_TRIO	126..273	CDD:459890	43/187 (23%)
TTPA	NP_001400347.1	CRAL_TRIO_N	<40..73	CDD:215024	12/25 (48%)
		CRAL_TRIO	159..286	CDD:459890	32/127 (25%)