DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10657 and sec14l8

DIOPT Version :9

Sequence 1:	NP_648579.3	Gene:	CG10657 / 39423	FlyBaseID:	FBgn0036289	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_001093463.1	Gene:	sec14l8 / 558964	ZFINID:	ZDB-GENE-060526-180	Length:	395	Species:	Danio rerio

Alignment Length:	250	Identity:	57/250 - (22%)
Similarity:	105/250 - (42%)	Gaps:	33/250 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 QALAQFREWIEKHPHIRKCRTDT-VFLLRFLRTKKFSVPSACEMLERYLTIRQ------LFPQWF 109
            :|||||||.::  ..:.:|.:.: .||||:||.:.|::..:..||.:::..|:      :..:|
Zfish    14 EALAQFREKVQ--DVLPQCPSQSDHFLLRWLRARNFNLQKSEAMLRKHIEFRKHMKVDTITTEW- 75

  Fly   110 KQLDINDPAINEIFENGYLVPLPQRDSTGRQVIFSVAAKFDP--YKFTSVQMARVHSLV--CEAL 170
                    .:.|:.:......:...|..|..|.:.|....||  ...::.:...:.|.|  ||.|
Zfish    76 --------QVPEVIDKYLSGGMCGHDREGSPVWYDVIGPLDPKGLMHSASKQDLIKSKVRDCEIL 132

  Fly   171 LDDEDSQ-------VAGYVYINDESGMNMGFVSLWSLTDLRSIVKCIQNSTPMRHKETHFVNIPH 228
            ..|.|.|       :.....:.|..|:.|..:...::.....::...:::.|...|....:..|.
Zfish   133 QKDCDRQSERLGRNIESITMVYDCEGLGMKHLYKPAIETYGEVLTMFEDNYPEGLKRLFVIKAPK 197

  Fly   229 YANRIIELGVSMLSDKLKKRIIVHKN--VDILKTKIDPAILPKEYGG--TVPIAD 279
            .......|....||:..::::||..:  .::|:..|||..||..|||  |.|..|
Zfish   198 LFPVAYNLVKHFLSEDTRRKVIVLGSNWQEVLQKYIDPEELPAYYGGKLTDPDGD 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10657	NP_648579.3	CRAL_TRIO_N	52..98	CDD:215024	17/46 (37%)
CG10657	NP_648579.3	CRAL_TRIO	126..274	CDD:279044	34/162 (21%)
sec14l8	NP_001093463.1	CRAL_TRIO_N	13..59	CDD:215024	17/46 (37%)
		SEC14	78..246	CDD:214706	35/167 (21%)
		GOLD_2	304..382	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810