DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10657 and Ku80

DIOPT Version :9

Sequence 1:	NP_648579.3	Gene:	CG10657 / 39423	FlyBaseID:	FBgn0036289	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_609767.2	Gene:	Ku80 / 34930	FlyBaseID:	FBgn0041627	Length:	699	Species:	Drosophila melanogaster

Alignment Length:	232	Identity:	47/232 - (20%)
Similarity:	86/232 - (37%)	Gaps:	75/232 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 RFLRTKKFS-----VPSACEMLERYLT--IRQLFP-----QWFKQLDINDPAINEIFENGYLV-- 129
            :.|:.|.|:     ||...|...:...  :::|||     .|.::|...:.|     |||..|
  Fly   485 KMLKDKNFADVFWRVPDPLEEKSKRAAAIVKKLFPLRYSRAWQEKLLAKEQA-----ENGVAVKS 544

  Fly   130 -------PLPQRDSTG--------RQVIFSV-----AAKFDPYKFTSVQMARVHSLVCEALLDDE 174
                   |||. |..|        |:|:.||     |.:.|         ||..:|..
  Fly   545 EPAEKEIPLPS-DGVGLIDPISDFRRVLASVHTISNATERD---------ARFQALAA------- 592

  Fly   175 DSQVAGYVYINDESGMNMGFVSLWSLTDLRSIVK--CIQNSTPMRHKETHFVNIPHYANRIIELG 237
            |::|. .:.:......|:|     .|.:|.::.:  ||..:|        |:....:|..:.::.
  Fly   593 DTRVV-IITLLQRRKQNIG-----QLGELITLYRQSCIDFNT--------FLEYDKFAEELKKIA 643

  Fly   238 VSMLSDKLKKRIIVHKNVDIL---KTKIDPAILPKEY 271
            ::....:..:.::|.|.:..|   :..:|..:..|.|
  Fly   644 LAKNRSEFWQDVMVDKQLGPLVLGEPTLDDELALKAY 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10657	NP_648579.3	CRAL_TRIO_N	52..98	CDD:215024	6/23 (26%)
CG10657	NP_648579.3	CRAL_TRIO	126..274	CDD:279044	33/173 (19%)
Ku80	NP_609767.2	Ku_N	7..213	CDD:281693
		KU80	221..524	CDD:238445	9/38 (24%)
		Ku_PK_bind	562..663	CDD:285938	22/130 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900