DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10657 and retm

DIOPT Version :9

Sequence 1:	NP_648579.3	Gene:	CG10657 / 39423	FlyBaseID:	FBgn0036289	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	58/269 - (21%)
Similarity:	96/269 - (35%)	Gaps:	64/269 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 LLRFLRTKKFSVPSACEML------ERYLTIRQLFPQWFKQLDINDPA-INEIFENGYLVPLPQR 134
            :||||..:.:.|..|..||      .|...|..|..::.|      || :.|.|..|:    ...
  Fly   247 ILRFLAARDWHVSQAYAMLCDSLRWRREHRIDALLAEYSK------PAVVVEHFPGGW----HHL 301

  Fly   135 DSTGRQVIFSVAAKFDP---YKFTSVQ-MARVHSLVCEALLD--DEDSQ-----VAGYVYINDES 188
            |..||.|........|.   .|...:. :.|:...:||..:.  :|.::     |..:..:.|..
  Fly   302 DKDGRPVYILRLGHMDVKGLLKSLGMDGLLRLALHICEEGIQKINESAERLEKPVLNWSLLVDLE 366

  Fly   189 GMNMGFVSLW--SLTDLRSIVKCIQNSTPMRHKETHFVNIPHYANRIIELG---VSMLSDKLKKR 248
            |::|.  .||  .:..|.:|::.::.:.|........|..|    |:..:.   ||...|:..:.
  Fly   367 GLSMR--HLWRPGIKALLNIIETVERNYPETMGRVLVVRAP----RVFPIAWTIVSAFIDEHTRS 425

  Fly   249 IIVHKNVDILKTK------IDPAILPKEYGGTVPIADMIAQ--------FKQKLQQRRAAILALD 299
            ..:....|....|      :|..|:|...||  |...||.:        :|..         :|:
  Fly   426 KFLFYGPDCAHMKDGLAQYLDEEIVPDFLGG--PCKTMIHEGGLVPKTLYKMN---------SLE 479

  Fly   300 DMQIEVTKD 308
            |...|||.:
  Fly   480 DHDDEVTAE 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10657	NP_648579.3	CRAL_TRIO_N	52..98	CDD:215024	8/26 (31%)
CG10657	NP_648579.3	CRAL_TRIO	126..274	CDD:279044	32/169 (19%)
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	8/20 (40%)
		CRAL_TRIO	293..456	CDD:279044	32/172 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810