Protein Alignment CG10657 and SEC14L3

DIOPT Version :10

• Sequence 1: NP_648579.3
• Gene: CG10657 / 39423
• FlyBaseID: FBgn0036289
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: XP_011528430.1
• Gene: SEC14L3 / 266629
• HGNCID: 18655
• Length: 412
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 62/261 - (23%)
• Similarity: 107/261 - (40%)
• Gaps: 58/261 - (22%)

  Fly    52 QALAQFREWIE------KHPHIRKCRTDTVFLLRFLRTKKFSVPSACEMLERYLTIRQLFPQWFK 110
            :.||:|||.::      .:|       |..||||:||.:.|.:..:..:|.:|:..|       |
Human    14 ETLAKFRENVQDVLPALPNP-------DDYFLLRWLRARNFDLQKSEALLRKYMEFR-------K 64

  Fly   111 QLDIN------DPAINEIFENGYLVPLPQRDSTGRQVIFSVAAKFDP----YKFTSVQMARVHSL 165
            .:||:      .|.:.:.:..|.|...   |..|..|.:.:....||    :..|...:.:....
Human    65 TMDIDHILDWQPPEVIQKYMPGGLCGY---DRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMR 126

  Fly   166 VCEALLDDEDSQ-------VAGYVYINDESGMNMGFVSLWSLTDLRSIVKCIQNSTPM---RHKE 220
            .||.:|.:.|.|       :...|.|.|..|  :|....|     :.:|:..|....:   .:.|
Human   127 DCERILHECDLQTERLGKKIETIVMIFDCEG--LGLKHFW-----KPLVEVYQEFFGLLEENYPE 184

  Fly   221 THFVNIPHYANRIIELGVSM----LSDKLKKRIIVHKN---VDILKTKIDPAILPKEYGGTVPIA 278
            |....:...|.::..:|.::    ||:..:::|||..|   ..:||. |.|..||.::|||:...
Human   185 TLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIIVLGNNWKEGLLKL-ISPEELPAQFGGTLTDP 248

  Fly   279 D 279
            |
Human   249 D 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10657	NP_648579.3	CRAL_TRIO_N	52..98	CDD:215024	15/51 (29%)
		CRAL_TRIO	126..273	CDD:459890	37/167 (22%)
SEC14L3	XP_011528430.1	CRAL_TRIO_N	13..59	CDD:215024	15/51 (29%)
		SEC14	76..245	CDD:214706	40/179 (22%)