DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10657 and Ttpa

DIOPT Version :9

Sequence 1:	NP_648579.3	Gene:	CG10657 / 39423	FlyBaseID:	FBgn0036289	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_037180.1	Gene:	Ttpa / 25571	RGDID:	3915	Length:	278	Species:	Rattus norvegicus

Alignment Length:	254	Identity:	67/254 - (26%)
Similarity:	120/254 - (47%)	Gaps:	13/254 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 VAKEELHEDEN---IRRQALAQFREWIEKH--PHIRKCRTDTVFLLRFLRTKKFSVPSACEMLER 97
            |..::|:|..:   :.:..||:.|...::.  |...:..|| .|||||||.:.|.:..|..:::.
  Rat     9 VVGKQLNEQPDHSPLVQPGLAELRRRAQEEGVPETPQPLTD-AFLLRFLRARDFDLDLAWRLMKN 72

  Fly    98 YLTIRQLFPQWFKQLDINDPAINEIFENGYLVPLPQRDSTGRQVIFSVAAKFDPYKFTSVQMARV 162
            |...|...|:  ...|::..:|..:.:.||...|..||.||.:|:....:.:||..||:..:.||
  Rat    73 YYKWRAECPE--LSADLHPRSILGLLKAGYHGVLRSRDPTGSRVLIYRISYWDPKVFTAYDVFRV 135

  Fly   163 HSLVCEALLDDEDSQVAGYVYINDESGMNMGFVSLWSLTDLRSIVKCIQNSTPMRHKETHFVNIP 227
            ..:..|.::.:.::|..|...|.|..|..:......:.:..:.|...:.:|.|::.:..|.:|.|
  Rat   136 SLITSELIVQEVETQRNGVKAIFDLEGWQISHAFQITPSVAKKIAAVVTDSFPLKVRGIHLINEP 200

  Fly   228 HYANRIIELGVSMLSDKLKKRIIVHKNVDILKTKI---DPAILPKEYGGTVPIADMIAQ 283
            ...:.:..:....|::|:|.||.:|.|  ..|:.:   .|.|||.||||.....:.|.|
  Rat   201 VIFHAVFSMIKPFLTEKIKGRIHLHGN--NYKSSLLQHFPDILPLEYGGNESSMEDICQ 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10657	NP_648579.3	CRAL_TRIO_N	52..98	CDD:215024	15/47 (32%)
CG10657	NP_648579.3	CRAL_TRIO	126..274	CDD:279044	41/150 (27%)
Ttpa	NP_037180.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22		3/12 (25%)
		CRAL_TRIO_N	25..73	CDD:215024	15/48 (31%)
		CRAL_TRIO	99..248	CDD:395525	41/150 (27%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	208..211		0/2 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820