Protein Alignment CG10657 and SEC14L2

DIOPT Version :10

• Sequence 1: NP_648579.3
• Gene: CG10657 / 39423
• FlyBaseID: FBgn0036289
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_036561.1
• Gene: SEC14L2 / 23541
• HGNCID: 10699
• Length: 403
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 63/266 - (23%)
• Similarity: 106/266 - (39%)
• Gaps: 46/266 - (17%)

  Fly    50 RRQALAQFREWIE------KHPHIRKCRTDTVFLLRFLRTKKFSVPSACEMLERYLTIRQLFPQW 108
            :::|||:|||.::      .:|       |..||||:||.:.|.:..:..||.:::..|
Human    12 QKEALAKFRENVQDVLPALPNP-------DDYFLLRWLRARSFDLQKSEAMLRKHVEFR------ 63

  Fly   109 FKQLDIND------PAINEIFENGYLVPLPQRDSTGRQVIFSVAAKFDP----YKFTSVQMARVH 163
             ||.||::      |.:.:.:.:|.:...   |..|..|.:.:....|.    :..:...:.|..
Human    64 -KQKDIDNIISWQPPEVIQQYLSGGMCGY---DLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTK 124

  Fly   164 SLVCEALLDDEDSQ-------VAGYVYINDESGMNMGFVSLW--SLTDLRSIVKCIQNSTPMRHK 219
            ...||.||.:...|       |.....|.|..|  :|...||  ::......:...:.:.|...|
Human   125 MRECELLLQECAHQTTKLGRKVETITIIYDCEG--LGLKHLWKPAVEAYGEFLCMFEENYPETLK 187

  Fly   220 ETHFVNIPHYANRIIELGVSMLSDKLKKRIIV--HKNVDILKTKIDPAILPKEYGGTVPIADMIA 282
            ....|..|........|....||:..:|:|:|  ....::|...|.|..:|.|||||:...|...
Human   188 RLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVEYGGTMTDPDGNP 252

  Fly   283 QFKQKL 288
            :.|.|:
Human   253 KCKSKI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10657	NP_648579.3	CRAL_TRIO_N	52..98	CDD:215024	17/51 (33%)
		CRAL_TRIO	126..273	CDD:459890	34/161 (21%)
SEC14L2	NP_036561.1	CRAL_TRIO_N	13..59	CDD:215024	17/52 (33%)
		SEC14	76..244	CDD:214706	36/172 (21%)