DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10657 and SEC14L2

DIOPT Version :9

Sequence 1:NP_648579.3 Gene:CG10657 / 39423 FlyBaseID:FBgn0036289 Length:334 Species:Drosophila melanogaster
Sequence 2:NP_036561.1 Gene:SEC14L2 / 23541 HGNCID:10699 Length:403 Species:Homo sapiens


Alignment Length:266 Identity:63/266 - (23%)
Similarity:106/266 - (39%) Gaps:46/266 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 RRQALAQFREWIE------KHPHIRKCRTDTVFLLRFLRTKKFSVPSACEMLERYLTIRQLFPQW 108
            :::|||:|||.::      .:|       |..||||:||.:.|.:..:..||.:::..|      
Human    12 QKEALAKFRENVQDVLPALPNP-------DDYFLLRWLRARSFDLQKSEAMLRKHVEFR------ 63

  Fly   109 FKQLDIND------PAINEIFENGYLVPLPQRDSTGRQVIFSVAAKFDP----YKFTSVQMARVH 163
             ||.||::      |.:.:.:.:|.:...   |..|..|.:.:....|.    :..:...:.|..
Human    64 -KQKDIDNIISWQPPEVIQQYLSGGMCGY---DLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTK 124

  Fly   164 SLVCEALLDDEDSQ-------VAGYVYINDESGMNMGFVSLW--SLTDLRSIVKCIQNSTPMRHK 219
            ...||.||.:...|       |.....|.|..|  :|...||  ::......:...:.:.|...|
Human   125 MRECELLLQECAHQTTKLGRKVETITIIYDCEG--LGLKHLWKPAVEAYGEFLCMFEENYPETLK 187

  Fly   220 ETHFVNIPHYANRIIELGVSMLSDKLKKRIIV--HKNVDILKTKIDPAILPKEYGGTVPIADMIA 282
            ....|..|........|....||:..:|:|:|  ....::|...|.|..:|.|||||:...|...
Human   188 RLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVEYGGTMTDPDGNP 252

  Fly   283 QFKQKL 288
            :.|.|:
Human   253 KCKSKI 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10657NP_648579.3 CRAL_TRIO_N 52..98 CDD:215024 17/51 (33%)
CRAL_TRIO 126..274 CDD:279044 35/162 (22%)
SEC14L2NP_036561.1 CRAL_TRIO_N 13..59 CDD:215024 17/52 (33%)
SEC14 76..244 CDD:214706 36/172 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1471
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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