DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10657 and sec14l1

DIOPT Version :9

Sequence 1:	NP_648579.3	Gene:	CG10657 / 39423	FlyBaseID:	FBgn0036289	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	XP_012825399.2	Gene:	sec14l1 / 100124776	XenbaseID:	XB-GENE-5823346	Length:	717	Species:	Xenopus tropicalis

Alignment Length:	359	Identity:	66/359 - (18%)
Similarity:	113/359 - (31%)	Gaps:	146/359 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QQPKLSGPAASSGG------------------DYDYPYVCGLSPAMKLVAKEELHEDENIRRQAL 54
            :|....||..:..|                  ||...|:..|:|               ::..||
Frog   206 EQTASQGPCKADAGSHSLAAEPSTPDTDKLEADYIERYLGQLTP---------------MQESAL 255

  Fly    55 AQFREWIE------------------KHPHIRKCRTDTVFLLRFLRTKKFSVPSACEMLERYLTI 101
            ...|:|::                  |..||          |||||.:.|::..|.|||.:.|:
Frog   256 IHLRQWLQETHKGKSEAGEWKPEKIPKDEHI----------LRFLRARDFNMEKAREMLCQSLS- 309

  Fly   102 RQLFPQWFKQLDIN-------DPAINEIFENG------------YLVPLPQRDSTGRQVIFSVAA 147
                  |.||..::       .|.:.|.:..|            |::.|.|.|:.|
Frog   310 ------WRKQHQVDYILQTWQPPRVLEEYYAGGWHYHDKDGRPLYILRLGQVDTKG--------- 359

  Fly   148 KFDPYKFTSVQMARVHSLVCEALLD-----DEDSQ-------------VAGYVYINDESGMNMGF 194
                         .|.:|..||:|.     :|:.|             :..:..:.|..|:||.
Frog   360 -------------LVKALGEEAILRHVLSINEEGQKRCEENTRQFGRPIWSWTCLVDLEGLNMR- 410

  Fly   195 VSLW--SLTDLRSIVKCIQNSTPMRHKETHFVNIPHYANRIIELGVSMLSDKLKKRIIVHKN--- 254
             .||  .:..|..|::.::.:.|........|..|.....:..|....:::..:::.:::..
Frog   411 -HLWRPGVKALLRIIEVVEANYPETLGRLLIVRAPRVFPVLWTLVSPFINENSRQKFLIYSGNNY 474

  Fly   255 ------VDILKTKIDPAILPKE------YGGTVP 276
                  .|.:..:|.|..|..|      .||.||
Frog   475 QGPGGIADYVDKEIVPDFLGGECVCNIPEGGLVP 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10657	NP_648579.3	CRAL_TRIO_N	52..98	CDD:215024	17/63 (27%)
CG10657	NP_648579.3	CRAL_TRIO	126..274	CDD:279044	31/194 (16%)
sec14l1	XP_012825399.2	PRELI	17..173	CDD:398400
		CRAL_TRIO_N	252..307	CDD:215024	17/64 (27%)
		CRAL_TRIO	332..496	CDD:395525	29/187 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910