Protein Alignment CG10663 and KLK10

DIOPT Version :10

• Sequence 1: NP_001097592.1
• Gene: CG10663 / 39421
• FlyBaseID: FBgn0036287
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: NP_002767.2
• Gene: KLK10 / 5655
• HGNCID: 6358
• Length: 276
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 78/279 - (27%)
• Similarity: 126/279 - (45%)
• Gaps: 48/279 - (17%)

  Fly   494 SGTGRRSMSNMLKII------------------------GGRAARKGEWPWQVAILNRFKEAFCG 534
            :.:|.|:::.:|.::                        |...|| |..||||::.|.. ...|.
Human    10 AASGARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCAR-GSQPWQVSLFNGL-SFHCA 72

  Fly   535 GTLIAPRWVLTAAHCVRKVLFVRIGEHNLNYEDGTEIQLRVMKSYTHPNF--------DKRTVDS 591
            |.|:...||||||||..|.|:.|:|:.:|....|.::: |..:|..||.:        .:||.:.
Human    73 GVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLR-RTTRSVVHPKYHQGSGPILPRRTDEH 136

  Fly   592 DVALLRLPKAVNATTWIGYSCLPQPFQALPKNVDCTIIGWGKRRNRDATGTSVLHKATVPIIPMQ 656
            |:.||:|.:.|.....:  ..|..|::.......|.:.|||....|.......|..:::.|:..:
Human   137 DLMLLKLARPVVLGPRV--RALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPK 199

  Fly   657 NCRKVYYDYTITKNMFCAGHQKGHIDTCAGDSGGPLLCRDTTKPNHPWTIFGITSFG-DGCAQRN 720
            .| :|:|...:|.||.|||..:|. |.|..||||||:|.:|.:        ||.|:| ..|....
Human   200 EC-EVFYPGVVTNNMICAGLDRGQ-DPCQSDSGGPLVCDETLQ--------GILSWGVYPCGSAQ 254

  Fly   721 KFGIYAKVPNYVDWVWSVV 739
            ...:|.::..|:.|:..|:
Human   255 HPAVYTQICKYMSWINKVI 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10663	NP_001097592.1	Tryp_SPc	506..735	CDD:214473	73/261 (28%)
KLK10	NP_002767.2	Tryp_SPc	49..272	CDD:238113	74/237 (31%)