DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10663 and F12

DIOPT Version :9

Sequence 1:NP_001097592.1 Gene:CG10663 / 39421 FlyBaseID:FBgn0036287 Length:748 Species:Drosophila melanogaster
Sequence 2:NP_000496.2 Gene:F12 / 2161 HGNCID:3530 Length:615 Species:Homo sapiens


Alignment Length:310 Identity:99/310 - (31%)
Similarity:148/310 - (47%) Gaps:39/310 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   438 PAFETRPGSGSPANAMRRMQSEQPEVSMNDLNYIMTGKGYRGPEYTPLKLSCGIVRSGTGRRSMS 502
            |...|.|.|.:| .|:...:.:.|.::.|            ||      ||||    ...|:|:|
Human   327 PTTRTPPQSQTP-GALPAKREQPPSLTRN------------GP------LSCG----QRLRKSLS 368

  Fly   503 NMLKIIGGRAARKGEWPWQVAILNRFKEAFCGGTLIAPRWVLTAAHCVR-----KVLFVRIGEHN 562
            :|.:::||..|.:|..|:..|:.  :..:||.|:||||.||||||||::     :.|.|.:|:..
Human   369 SMTRVVGGLVALRGAHPYIAALY--WGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 431

  Fly   563 LNYEDGTEIQLRVMKSY-THPNFDKRTVDSDVALLRLPKAVNA-----TTWIGYSCLPQPFQALP 621
            .|: .....|...::|| .|..|...:...|:|||||.:..:.     :.::...|||.......
Human   432 RNH-SCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSGAARPS 495

  Fly   622 KNVDCTIIGWGKRRNRDATGTSVLHKATVPIIPMQNCRKV-YYDYTITKNMFCAGHQKGHIDTCA 685
            :...|.:.|||.:........|.|.:|.||.:.::.|... .:..:|...|.|||..:|..|.|.
Human   496 ETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTDACQ 560

  Fly   686 GDSGGPLLCRDTTKPNHPWTIFGITSFGDGCAQRNKFGIYAKVPNYVDWV 735
            |||||||:|.|...... .|:.||.|:|.||..|||.|:|..|..|:.|:
Human   561 GDSGGPLVCEDQAAERR-LTLQGIISWGSGCGDRNKPGVYTDVAYYLAWI 609

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10663NP_001097592.1 Tryp_SPc 506..735 CDD:214473 80/240 (33%)
Tryp_SPc 507..735 CDD:238113 80/239 (33%)
F12NP_000496.2 FN2 41..88 CDD:128373
EGF_CA 96..131 CDD:238011
FN1 133..173 CDD:238018
EGF 178..206 CDD:278437
Kringle 217..295 CDD:278480
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 298..359 11/50 (22%)
Tryp_SPc 372..609 CDD:214473 80/240 (33%)
Tryp_SPc 373..612 CDD:238113 81/241 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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