DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10663 and si:dkey-32n7.7

DIOPT Version :9

Sequence 1:	NP_001097592.1	Gene:	CG10663 / 39421	FlyBaseID:	FBgn0036287	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	XP_021335883.1	Gene:	si:dkey-32n7.7 / 108191692	ZFINID:	ZDB-GENE-121214-179	Length:	609	Species:	Danio rerio

Alignment Length:	549	Identity:	133/549 - (24%)
Similarity:	200/549 - (36%)	Gaps:	127/549 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 PGKDIF------SEE------DVEDELEPEPDE-------------------DLISSDEQGDFFV 282
            ||:.:|      :||      |.|||:.|:.|:                   |.|..:..||.
Zfish    54 PGRWVFRVDGRSNEEIFYPYGDAEDEINPQSDDGSSPPIPLLQSFVYFGNTYDTIFVNNNGDL-- 116

  Fly   283 LKHHRHRRRQNHRRPSHRKPPKEEDYDDSDFVDFGERKSLRHRHLGEDSSVEGDVFQYEDFDLPD 347
                      ...:|.|:       |:..:|..:..|..:.......::.:||.: .|......|
Zfish   117 ----------TFDKPLHQ-------YNPDNFPAYSTRDIIAPLWTDINNGMEGTI-SYRQVTNGD 163

  Fly   348 TMYADSQESEGEFRNI----TWMQPAKDGIALRRRKVYSKWSRWTKCSPKCTTRRYKKCRIMDQC 408
            .:...|::....|.|:    :|:             ..:.|.:......:.:...::...:.|:.
Zfish   164 ILNRASKDINRYFPNLNFSASWV-------------FIATWDKVPYYGYRESESTFQVVLVSDKK 215

  Fly   409 GREVLREIAY-CYTE---------GSFCQQWLQTQFQKTPAFE-TRPGSGSPANAMRRM------ 456
            ....|....| .||:         ||       |.|...|..: |.....|..|...|.
Zfish   216 RSFTLMHYDYITYTQSAESGYDTNGS-------TVFYSIPVSDVTNLPYTSNVNVKGRWVFRVDN 273

  Fly   457 QSEQPEVSMNDLNYIMTGKGYRGPEYTPLKLSCGI--VRSGTGRRSMSNMLKIIGGRAARKGEWP 519
            .||.....:|..:..:.         :|....|||  |.|..|         .:||:.:....||
Zfish   274 SSEVKGSCINTNSQALD---------SPSAAVCGIIPVNSSNG---------TVGGQNSSAVHWP 320

  Fly   520 WQVAILNRFKEAFCGGTLIAPRWVLTAAHCVRK-----VLFVRIGEHNLNYEDGTEIQLRVMKSY 579
            || |.|..:....|||:||...|||:||||...     .|.|.:|....|..|.:.|...|....
Zfish   321 WQ-ASLYWYSGQTCGGSLINKEWVLSAAHCFNGQRNGFYLTVILGPKTQNKYDPSRISRSVKAVI 384

  Fly   580 THPNFDKRTVDSDVALLRLPKAVNATTWIGYSCLPQPFQALPKNVDCTIIGWGKRRNRDAT---G 641
            .||.::..|.|:|:||:||...:..|..|...||.........:.:..|..|  |...|..   .
Zfish   385 KHPYYNPNTNDNDIALVRLSFPITFTDSIRPVCLAAEGSVFNSDTESWITTW--RNISDGVPLPS 447

  Fly   642 TSVLHKATVPIIPMQNCRKVYYDYTITKNMFCAGHQKGHIDTCAGDSGGPLLCRDTTKPNHPWTI 706
            ..:..:..||:|..:.|..:|...:||.||.|||..|...|.|.||||||::...::    .|..
Zfish   448 PKIFQEVEVPVIGNRQCNCLYGVGSITDNMICAGLLKEGKDLCQGDSGGPMVSNQSS----VWVQ 508

  Fly   707 FGITSFGDGCAQRNKFGIYAKVPNYVDWV 735
            .||.|||.||||....|:|.:|..|.:|:
Zfish   509 SGIVSFGSGCAQSEFPGVYTRVSRYQEWI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10663	NP_001097592.1	Tryp_SPc	506..735	CDD:214473	79/236 (33%)
CG10663	NP_001097592.1	Tryp_SPc	507..735	CDD:238113	79/235 (34%)
si:dkey-32n7.7	XP_021335883.1	NIDO	4..63	CDD:310601	3/8 (38%)
		NIDO	141..272	CDD:322035	23/151 (15%)
		Tryp_SPc	309..537	CDD:238113	79/234 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910