Protein Alignment eyg and Pax4

DIOPT Version :9

• Sequence 1: NP_001014582.1
• Gene: eyg / 39419
• FlyBaseID: FBgn0000625
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_113987.1
• Gene: Pax4 / 83630
• RGDID: 620433
• Length: 349
• Species: Rattus norvegicus
• Alignment Length: 410
• Identity: 132/410 - (32%)
• Similarity: 169/410 - (41%)
• Gaps: 140/410 - (34%)

  Fly   130 GLRGYDIAQHMLTQQGAVSKLLGS------LRPPGLIGGSKPKVATPTVVSKIEQYKRENPTIFA 188
            |:|..||::.:....|.|||:||.      |.|.| ||||||::|||.||::|.|.|.|.|.:||
  Rat    37 GMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKG-IGGSKPRLATPAVVARIAQLKDEYPALFA 100

  Fly   189 WEIRERLISEGVCTNATAPSVSSINRILRNRAAERVATEFARTAAYGLYPPPPHPYGSFTWHPAG 253
            |||:.:|.:||:||...|||||||||:|      |...|..|.....|..|
  Rat   101 WEIQRQLCAEGLCTQDKAPSVSSINRVL------RALQEDQRLHWTQLRSP-------------- 145

  Fly   254 NVPGGQGVPPPPPPSALWSVAAPTLANLPPSAASAVPVSTCGSLSSAHLMAGGAGGTPTNRAISP 318
                              :|.||.|    ||     |.|.|.:....|                |
  Rat   146 ------------------AVLAPAL----PS-----PHSNCEAPRGPH----------------P 167

  Fly   319 GSGSHDTLESADENRHIDSDYLDDDDEPKFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSS 383
            |: ||                          ||||.|||.|.|.|||||.:..||....|.:|::
  Rat   168 GT-SH--------------------------RNRTIFSPGQAEALEKEFQRGQYPDSVVRGKLAA 205

  Fly   384 RTSLSEARVQVWFSNRRAKWRRHQRMNLLKRQRSSPA----------NP--LHSQQSNDAPASSP 436
            .|||.|..|:||||||||||||.::   ||.:...|.          :|  :.:|||   |.|.|
  Rat   206 ATSLPEDTVRVWFSNRRAKWRRQEK---LKWETQMPGASQDLMVPKDSPGIISAQQS---PGSVP 264

  Fly   437 T---------------------PSNHSSASTS-APVAPVPPPQQPLPLCGDHSPQGPPPSVLLHP 479
            :                     |...||.:|| |.:.|.......||:......:...|.:..||
  Rat   265 SAALPVLEQLNPSFCQLCWGAVPDRCSSDTTSQACLQPYWECHSLLPVASSSYMEFAWPCLTTHP 329

  Fly   480 LH---GPPGGHHHHHPLHLP 496
            :|   |.||.....:.||.|
  Rat   330 VHHLIGGPGQAPSTYYLHWP 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_001014582.1	HTH	120..217	CDD:304362	48/92 (52%)
		Homeobox	352..404	CDD:278475	30/51 (59%)
Pax4	NP_113987.1	PAX	5..129	CDD:128645	49/98 (50%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	8..64		10/26 (38%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	83..131		28/53 (53%)
		Homeobox	174..226	CDD:278475	30/51 (59%)
		Transcription repression	278..349		18/70 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810