Protein Alignment eyg and Pax8

DIOPT Version :9

• Sequence 1: NP_001014582.1
• Gene: eyg / 39419
• FlyBaseID: FBgn0000625
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_112403.2
• Gene: Pax8 / 81819
• RGDID: 620434
• Length: 457
• Species: Rattus norvegicus
• Alignment Length: 470
• Identity: 135/470 - (28%)
• Similarity: 190/470 - (40%)
• Gaps: 148/470 - (31%)

  Fly    88 IPPGFGGGGSTGGIPHGAGGPTGSTLNTLMSQHRLLEFSRFGGLRGYDIAQHMLTQQGAVSKLL- 151
            |..|.||....||     ....|..|..::.| |:::.:. .|:|..||::.:....|.|||:|
  Rat     6 IRSGHGGLNQLGG-----AFVNGRPLPEVVRQ-RIVDLAH-QGVRPCDISRQLRVSHGCVSKILG 63

  Fly   152 -----GSLRPPGLIGGSKPKVATPTVVSKIEQYKRENPTIFAWEIRERLISEGVCTNATAPSVSS 211
                 ||:| ||:|||||||||||.||.||..|||:|||:||||||:||::||||.|.|.|||||
  Rat    64 RYYETGSIR-PGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127

  Fly   212 INRILRNRAAER--------VATEFARTAAYGLYPPPPHPYGSFTWHPAGNVPGGQGVPPPPPPS 268
            ||||:|.:..:.        |||:..         .|.|..          :|.....||..|.|
  Rat   128 INRIIRTKVQQPFNLPMDSCVATKSL---------SPGHTL----------IPSSAVTPPESPQS 173

  Fly   269 ALWSVAAPTLANLPPSAASAVPVSTCGSLSSAHLMAGGAGGTPTNRAISPGSGSHDTLESADENR 333
                                      .||.|.:.:.|..|      ...|||.:...::.:|:
  Rat   174 --------------------------DSLGSTYSINGLLG------IAQPGSDNKRKMDDSDQ-- 204

  Fly   334 HIDSDYLDDDDE-----PKFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSS---------- 383
              ||..|..|.:     |:......||....||.||..|::.|||     |..:|
  Rat   205 --DSCRLSIDSQSSSSGPRKHLRTDTFGQHHLEPLECPFERQHYP-----EAYASPSHTKGEQGL 262

  Fly   384 ------RTSLSEARVQVWFSNR--RAKWRRHQRMNLLKRQRSSPANPLH-SQQSNDAPASSPTPS 439
                  .::|.:.:..:..||.  ......||...::    :.|.:|.. .|::.:..:||.|||
  Rat   263 YPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVV----ADPHSPYAIKQETPELSSSSSTPS 323

  Fly   440 NHSSASTSAPVAPVPPPQQPLPLCGDHSPQG---PPPSVLLH-----------------PLHGP- 483
            :.||::.           ..|...|...|.|   ||.:...|                 .:.||
  Rat   324 SLSSSAF-----------LDLQQVGSGGPAGASVPPFNAFSHAASVYGQFTGQALLSGREMVGPT 377

  Fly   484 -PGGHHHHHPLHLPT 497
             ||     :|.|:||
  Rat   378 LPG-----YPPHIPT 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_001014582.1	HTH	120..217	CDD:304362	59/102 (58%)
		Homeobox	352..404	CDD:278475	15/69 (22%)
Pax8	NP_112403.2	PAX	9..133	CDD:128645	67/131 (51%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	12..68		16/62 (26%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	87..135		34/47 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	159..226		19/112 (17%)
		Pax2_C	344..455	CDD:289189	11/49 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810