Protein Alignment eyg and alx1

DIOPT Version :10

• Sequence 1: NP_524042.2
• Gene: eyg / 39419
• FlyBaseID: FBgn0000625
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001038539.1
• Gene: alx1 / 565176
• ZFINID: ZDB-GENE-050419-191
• Length: 320
• Species: Danio rerio
• Alignment Length: 280
• Identity: 83/280 - (29%)
• Similarity: 112/280 - (40%)
• Gaps: 79/280 - (28%)

  Fly   298 SSAHLMAGGAGGTPTNRAISPGSGSHDTLESADENRHIDSDYLDDDDEPKFRRNRTTFSPEQLEE 362
            ||.|.|....     :..:||.:...|..:..:.....||:.    ...|.||:||||:..||||
Zfish    79 SSLHAMENCC-----SLRVSPATSGPDKTDLDELGEKCDSNV----SSSKKRRHRTTFTSAQLEE 134

  Fly   363 LEKEFDKSHYPCVSTRERLSSRTSLSEARVQVWFSNRRAKWRRHQRMNLLKRQRSS--------- 418
            |||.|.|:|||.|..||:|:.||.|:||||||||.|||||||:.:|...:::.:|.
Zfish   135 LEKVFQKTHYPDVYVREQLAMRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISM 199

  Fly   419 -PANPLHSQQSNDAPASSPTPSNHSSASTSAPVAPVPPPQQPLPLCGDHSPQGPPPSVLLHPLHG 482
             |....:||.||:....   ||..||..:|..:                 |:|.||.|.....|.
Zfish   200 LPRTDSYSQISNNLWTG---PSAGSSVVSSCMI-----------------PRGSPPCVTSPYPHS 244

  Fly   483 PPGGHHHHHPLHLPTHPAALQLLSHYHQQQQQQQQQQHQQQQQQHHQQQQQLSPSGCNPAANHLS 547
            |....|.:  :..|.|                               ||.|.       ..||:|
Zfish   245 PRAAEHGY--VGFPNH-------------------------------QQNQF-------GVNHVS 269

  Fly   548 MGGERSAFRSLVSSPSAAAF 567
            :....:......|:.|.|||
Zfish   270 LNNFFADSLLASSANSHAAF 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_524042.2	HTH_ARSR	120..217	CDD:481197
		Homeodomain	349..405	CDD:459649	39/55 (71%)
alx1	NP_001038539.1	Homeodomain	121..177	CDD:459649	39/55 (71%)
		Transactivation domain. /evidence=ECO:0000250|UniProtKB:Q63087	180..320		33/170 (19%)
		OAR	296..314	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	300..313