Protein Alignment eyg and otx2

DIOPT Version :10

• Sequence 1: NP_524042.2
• Gene: eyg / 39419
• FlyBaseID: FBgn0000625
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_012823826.1
• Gene: otx2 / 548931
• XenbaseID: XB-GENE-485220
• Length: 306
• Species: Xenopus tropicalis
• Alignment Length: 293
• Identity: 56/293 - (19%)
• Similarity: 102/293 - (34%)
• Gaps: 92/293 - (31%)

  Fly   271 IFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELV---ENLSQGNFTLRS 332
            |..||.:.:..|:..:|:..: |:.     .|:::.|......:...:||   :||..|...:..
 Frog   115 ILSGTSDLLLTFDEAEVRKII-RVC-----KGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAK 173

  Fly   333 MYDQFQCSL-----RIPL----NQLFSMLPGISAEMM-------PKGHGEESRVK---------- 371
            |.|:.|..|     |:.|    |.:..:||.:.:.|.       .|..|.|..:|
 Frog   174 MIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMS 238

  Fly   372 ---------------------------MKRYMTMMDSMTNKEL-----DSPNPKIFNESRIMRIA 404
                                       |||.:..:||..|:..     .|.:|....|..|.:|.
 Frog   239 AEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQIL 303

  Fly   405 RGSGRL-----VREVMEMLEEYKRIAK-TMKGIKIPKNGDMSKVIPPQMLKQMG-GMSGL----- 457
            ..:|::     .:|..|:|...|.:.: |.:...:...|..|..:..|..:|:. |:..|
 Frog   304 DEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGLDVLTAKVE 368

  Fly   458 -------------QSLMKQMGSAKDMMGMFGGG 477
                         ||:.|::.:|::.:....||
 Frog   369 NAARKLEAMTNSKQSIAKKIDAAQNWLADPNGG 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_524042.2	HTH_ARSR	120..217	CDD:481197
		Homeodomain	349..405	CDD:459649	18/104 (17%)
otx2	XP_012823826.1	Homeodomain	56..111	CDD:459649
		TF_Otx	170..251	CDD:427350	14/80 (18%)